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題 名 | Nasopharyngeal Carcinoma with Initial Presentation of Isolated Compressive Optic Neuropathy--A Case Report=以壓迫性視神經病變為初期臨床表現之鼻咽癌--病例報告 |
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作 者 | 張佩珍; 顏美媛; 林妍青; 王安國; | 書刊名 | 中華民國眼科醫學會雜誌 |
卷 期 | 46:1 2007.03[民96.03] |
頁 次 | 頁42-45 |
分類號 | 416.879 |
關鍵詞 | 壓迫性視神經病變; 鼻咽癌; Compressive optic neuropathy; Initial manifestation; Nasopharyngeal carcinoma; Orbital invasion; |
語 文 | 英文(English) |
中文摘要 | 目的:本文報告一例以壓迫性視神經病變為初期表現之鼻咽癌。 方法:病例報告。 結果:一位三十五歲女性病患因主訴右眼視力不佳而被發現有色彩視覺的減退與相對性傳入性瞳孔缺陷 (relative afferent papillary defect, RAPD),但並未伴隨有其他腦神經病變之徵候。電腦斷層及磁振造影檢查發現視神經被軟組織腫塊壓迫。神經影像學檢查顯示鼻咽癌經由翼窩 (pterygopalatine fossa)侵犯右側眼窩尖端 (orbital apex),並影響右側視神經,而其他的神經或血管組織仍是完整的。鼻咽組織的病理切片檢查結果顯示為一未分化之腺癌 (ulldifferentiated carcinoma)。接受化學治療之後,病人的右眼視力恢復到壹點零。 結論:鼻咽癌可能單獨以壓迫性視神經病變作為初期臨床表現。 |
英文摘要 | Purpose: To describe a case of nasopharyngeal carcinoma (NPC) with initial presentation of isolated compressive optic neuropathy. Method: Case report. Result: A 35-year-old female got impaired visual acuity, poor color vision and relative afferent pupillary defect in her right eye without other cranial nerve signs. Optic nerve compression by soft tissue mass was found in computed tomography (CT) and magnetic resonance imaging (MRI). Neuroimaging studies revealed right orbital invasion of NPC through the pterygopalatine fossa. Optic nerve was involved at the right orbital apex with sparing of the other neurovascular tissues. Nasopharyngeal biopsy showed an undifferentiated carcinoma. After chemotherapy, she recovered her vision to 20/20 in the right eye. Conclusion: NPC patient may present with an initial presentation of isolated compressive optic neuropathy. |
本系統中英文摘要資訊取自各篇刊載內容。