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題名 | Kwashiorkor and Concurrent Acquired Acrodermatitis Enteropathica in a Case with Hirschsprung's Disease--A Case Report and Review of the Literature=惡性營養不良症合併後天腸病性肢端皮膚炎於一先天性巨腸症患者--病例報告暨文獻回顧 |
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作者 | 劉懿珊; 羅珮瑜; 宗天一; 黃一菲; Liu, Yi-shan; Lo, Pei-yu; Tzung, Tien-yi; Huang, I-fei; |
期刊 | 中華皮膚科醫學雜誌 |
出版日期 | 20070300 |
卷期 | 25:1 2007.03[民96.03] |
頁次 | 頁43-47 |
分類號 | 415.71 |
語文 | eng |
關鍵詞 | 惡性營養不良症; 蛋白質; 腸病性肢端皮膚炎; 鋅; Kwashiorkor; Acrodermatitis enteropathica; Hirschsprung's disease; Zinc deficiency; |
中文摘要 | 惡性營養不良症是一種蛋白質能量營養不良的疾病,其具有獨特的“油漆層狀脫落”般的皮膚炎表現。惡性營養不良症的病人血清中鋅的濃度可能有低下的情形,然而,絕大部分的病人不會同時合併因鋅缺乏而引起的典型腸病性肢端皮膚炎。我們在此提出一同時合併惡性營養不良症及後天腸病性肢端皮膚炎的病例。一個兩歲八個月大男孩,本身是一位先天性巨腸症的患者,因小腸結腸炎而入院。十天後,他全身出現過度角化的深色斑塊,同時在身體的開口處出現對稱性脫屑糜爛溼疹性病灶。實驗室檢查的結果呈現低白蛋白血症與低血鋅的現象。經過人類白蛋白以及每日一次5mg葡萄糖酸鋅的補充後,臨床症狀在十天後即獲得緩解。 |
英文摘要 | Kwashiorkor is a form of protein-energy malnutrition with a characteristic "flaky paint" dermatosis. Patients with kwashiorkor may have a low serum level of zinc. However, most patients fail to show the typical cutaneous manifestation of zinc deficiency, namely, acrodermatitis enteropathica. We herein reported a patient with concurrent kwashiorkor and acquired acrodermatitis enteropathica. This 2-year-and-8-month-old boy, a case of Hirschsprung's disease, was admitted due to enterocolitis. Ten days after admission, generalized hyperkeratotic and hyperpigmented plaques with symmetrical scaly and erosive eczematous lesions around the body orifices were observed. Laboratory data revealed hypoalbuminemia (1.7 g/dL) and hypozincemia. After intravenous administration of human albumin together with zinc gluconate 5 mg once a day, his skin rash subsided gradually in ten days. |
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