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相關文獻
- Clinical Analysis of Pheochromocytoma/Paraganglioma in Southern Taiwan
- Blood Pressure Change in Patients with a Benign Adrenal Tumor after Unilateral Adrenalectomy
- Reversible Hypertensive Retinopathy in a Child with Bilateral Pheochromocytoma after Tumor Resection
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- Time to Normalization of Blood Pressure after an Adrenalectomy for Patients with Primary Aldosteronism
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- 嗜鉻細胞瘤之影像學診斷
- 腎上腺偶見瘤
頁籤選單縮合
題名 | Clinical Analysis of Pheochromocytoma/Paraganglioma in Southern Taiwan=南臺灣的嗜鉻細胞瘤/副神經瘤:二十三位病例的臨床分析和其他腎上腺腫瘤 |
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作者 | 黃國清; 王明誠; 吳安邦; 盧豐華; 曾進忠; 黃建鐘; Huang, Kuo-ching; Wang, Ming-cheng; Wu, An-bang; Lu, Feng-hwa; Tseng, Ching-chung; Huang, Jeng-jong; |
期刊 | 臺灣腎臟醫學會雜誌 |
出版日期 | 20060900 |
卷期 | 20:3 民95.09 |
頁次 | 頁166-174+228 |
分類號 | 415.934 |
語文 | eng |
關鍵詞 | 腎上腺腫瘤; 嗜鉻細胞瘤; 副神經瘤; 高血壓; 香草杏仁酸; 腎上腺切除術; VMA; Adrenal tumor; Pheochromocytoma; Paraganglioma; Hypertension; Vanillylmandelic acid; Adrenalectomy; |
中文摘要 | 嗜鉻細胞瘤(Pheochromocytoma)是一罕見會造成次發性高血壓的腫瘤,雖可以治癒;但若沒作正確的診斷,患者有致死之可能。我們回顧從1988年至2004年成大醫學中心登錄為腎上腺腫瘤的145名病患中,九位為神經母細胞瘤(neuroblastoma)的小孩,55位(懷疑)為腎上腺轉移(adrenal metastasis),42位為醛固酮產生腺瘤(aldosterone-producing adenoma)-男性11位和女性31位以及7位皮質醇分泌腺瘤(cortisolsecreting adenoma)之女性。此外,18例為嗜鉻細胞瘤和5例為副神經節瘤(paraganglioma),在這23位患者中,男女的比例相當;其中12位具有高血壓,除一位糖尿病併慢性腎功能不全患者接受腎上腺切除術之後,仍有高血壓;其餘的患者在術後,其高血壓都獲得治癒。共有14名患者曾檢驗尿中的香草杏仁酸(vanillylmandelic acid, VMA)之濃度,發現若是腫瘤越大,其VMA值會越高(r=0.5668, P<0.0434)。總之,本院的嗜鉻細胞瘤/副神經節瘤患者,在術後有很高的高血壓治癒率,且腫瘤之大小和尿中VMA的濃度有明顯相關性。 |
英文摘要 | Pheochromocytoma, albeit rare, is an important cause of secondary hypertension. Although potentially curable, it can be lethal if it goes unrecognized. We reviewed the medical charts of 145 patients with ICD-9 coded as adrenal tumors from 1988 to 2004. A total of 140 patients were enrolled in this study. Eighteen patients had Pheochromocytoma, and five patients had paraganglioma. Among these 23 Pheochromocytoma/paraganglioma patients, 13 cases had hypertension. A total of 12 received an operation and had no intra-operative mortality. Eleven patients became normotensive after operation. The other one, who was concomitant with diabetic nephropathy and chronic renal insufficiency, had persistent hypertension after operation and progressed to end-stage renal disease. Urinary levels of vanillylmandelic acid (VMA) were checked in 14 patients. Comparing the estimated tumor sizes with the urinary levels of VMA, larger masses had higher VMA levels (r=0.5668, P=0.0434). The Pheochromocytoma/paraganglioina had the variable clinical presentations and was a nearly curable hypertensive disease. Also, the urinary levels of VMA correlated with estimated tumor sizes. |
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