查詢結果分析
來源資料
頁籤選單縮合
題 名 | Acute Renal Failure in Burned Patients=燒燙傷患者合併急性腎衰竭之分析 |
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作 者 | 葉宏日; 陳永昌; 莊秀樹; 方基存; 黃秋錦; | 書刊名 | 臺灣腎臟醫學會雜誌 |
卷 期 | 14:1 民89.03 |
頁 次 | 頁17-22+43 |
分類號 | 415.815 |
關鍵詞 | 急性腎衰竭; 燒燙傷; 燒燙傷面積; 器官衰竭數; Acute renal failure; Burn; TBSA; Organ failure system; APACHE Ⅱ; APACHE Ⅲ; |
語 文 | 英文(English) |
中文摘要 | 背景:目前燒燙傷患者合併急性腎衰竭發生率已降低,可是一旦發生急性腎衰竭其死亡率仍然偏高,故我們設計本實驗來討論這個問題。方法:在這溯往性研究中,於1999年元月至1999年十二月,總共有一千兩百位燒燙傷患者,其中有十二位合併急性腎衰竭。我們收集並分析了這十二位患者的臨床資料和各種生化資料,來解答問題。結果:在此研究中,急性腎衰竭的發生率為百分之一。共有八位男性及四位女性,平均年齡為55.58 ± 20.13歲。住院死亡率為66.7%。在死亡與非死亡患者之間,年齡和性別並未達具統計意義的差別。這十二位燒燙傷患者之二度及三度燒燙傷面積,平均為45.25 ± 31.14%。當發生急性腎衰竭時,器官衰竭數平均為3.33 ± 1.50。急性腎衰竭發生日多在住院後第二週,多起因於敗血症及腎毒性藥物。在死亡患者發生急性腎衰竭時的器官辦竭數,APACHE Ⅱ、APACHEⅢ分數都較高。在這研究中指出,死亡率與較高的燒燙傷面積,器官衰竭數目,APACHEⅡ、APACHEⅢ分數有正相關。結論:目前燒燙傷患者合併急性腎衰竭發生率已降低,可是發生急性腎衰竭時其死亡率仍然偏高。急性腎衰竭為多重器官衰竭的表徵之一。急性腎衰竭本身不致致人於死,但會造成病人病情惡化及更複雜和難以處理的臨床狀況。 |
英文摘要 | Background: At the present time acute renal failure is a much less frequent complication in burned patients than it was in the past. Once acute renal failure has developed, it has an extremely high mortality rate. Methods: A retrospective review of 12 from a total of 1200 burned patients admitted to our burn unit between January 1999 and December 1999, experienced acute renal failure. Results: The incidence of acute renal failure in our population of burned is 1 per cent. There were 8 men and four women with a mean age of 55.58 ± 20.13 years. The overall hospital mortality rate was 66.7%. There were no significant differences between survivors and non-survivors in terms of age or gender. Mean second-or third-degree burned body surface, as evaluated by plastic surgeons upon arrival, was 45.25 ± 31.14 per cent of the total body surface area (TBSA). The mean number of failed organ at the time of acute renal failure was 3.33 ± 1.50. Acute renal failure mainly occurred in the second week following admission in relation to sepsis and nephrotoxic drugs. Death in most patients was related to higher failed organs, APACHEⅡ or APACHEⅢ scores on the first day of acute renal failure occurred. Our results indicated a significant rise in mortality rates associated with a higher TBSA, organ system failures, APACHEⅡ or Ⅲ scores among all patients. Conclusion: Acute renal failure is a relative rare event in severely burn unit patients. We conclude that mortality rate for acute renal failure in burn unit patients continues to be high. Our findings suggest that acute renal failure is usually a part of multiorgan failure complex. Renal failure alone should not kill these patients, bearing in mind that renal failure is often a part of this complex problem in these patients. |
本系統中英文摘要資訊取自各篇刊載內容。