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題名 | Acute Renal Failure after 5-Aminosalicylic Acid Therapy in a 47-Year-Old Woman with Ulcerative Colitis=潰瘍性結腸炎的47歲婦女在接受5-Aminosalicylic Acid治療後引發急性腎衰竭 |
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作者姓名(中文) | 林鈺琳; 馮祥華; 曾嶔元; | 書刊名 | 臺灣腎臟醫學會雜誌 |
卷期 | 19:2 民94.06 |
頁次 | 頁81-83+95 |
分類號 | 415.815 |
關鍵詞 | 急性腎衰竭; 急性腎間質組織腎炎; 5-aminosalicylic acid; Acute renal failure; Acute interstitial nephritis; |
語文 | 英文(English) |
英文摘要 | Inflammatory bowel disease such as ulcerative colitis and Crohn's disease is frequent treated first line by 5-aminosalicylic acid (5-ASA). Acute renal failure due to acute interstitial nephritis is an infrequent complication of 5-ASA therapy. In most reported cases of 5-ASA-induced interstitial nephritis, patients had taken the drug for 6 months or more before significant renal insufficiency was documented. We described a 47-year-old female with ulcerative colitis who suffered from symptomatic acute renal failure (BUN and serum creatinine were 51mg/dL and 5.2mg/dL) after one year 5-ASA therapy. Renal biopsy revealed acute interstitial nephritis. After discontinuation of 5-aminosalicylic acid, renal function returned to baseline four months later (BUN and serum creatinine are 26mg/dL and 1.1mg/dL). |
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