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題 名 | 八週間歇性低氧對葡萄糖耐受度與骨骼肌型態的影響=The Effects of Eight-week Intermittent Hypoxia on Glucose Tolerance and Skeletal Muscle Morphology |
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作 者 | 吳明杰; 蔡櫻蘭; 陳美枝; 蘇福新; 蔡一鳴; 郭家驊; | 書刊名 | 大專體育學刊 |
卷 期 | 7:4 民94.12 |
頁 次 | 頁151-160 |
分類號 | 528.9012 |
關鍵詞 | 間歇性低氧; 胰島素敏感度; 肌纖維大小; 微血管密度; Intermittent hypoxia; Insulin sensitivity; Fiber size; Capillary density; |
語 文 | 中文(Chinese) |
英文摘要 | This study investigated the effects of eight weeks' intermittent hypoxia (14% O2) on glucose tolerance and skeletal muscle morphology. Twenty-one Sprague-Dawley rats were matched for weight and assigned into three different treatments: control, one-hour hypoxia/day, and eight-hour hypoxia/day. The fiber type of soleus muscle was determined using the mATPase (pH4.6) and SDH method, and the capillary density was visualized using the AP method. Visceral fat weight, fasting blood glucose, fasting and postprandial serum insulin concentration in Group E were significantly lower than Group C during the OGTT. Group E had a significantly increased percentage of Type Ⅱa fiber and capillary density in soleus muscle than Group C, whereas the fiber size of soleus muscle of the former group decreased. Furthermore, significant correlations were found among abdominal fat weight (r=0.50, p.05), the fiber size of soleus muscle (r=-0.43, p<.05), and postprandial serum insulin concentration. It was concluded that intermittent hypoxia improved insulin sensitivity and the degree of improvement was determined by the effect of hypoxia duration on visceral fat weight and muscle fiber size. |
本系統中英文摘要資訊取自各篇刊載內容。