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題 名 | Multinucleate Cell Angiohistiocytoma: A Case Report=多核細胞血管組織球瘤--病例報告 |
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作 者 | 王靖博; 蘇信義; 吳育弘; 林揚志; | 書刊名 | 中華皮膚科醫學雜誌 |
卷 期 | 23:3 2005.09[民94.09] |
頁 次 | 頁154-157 |
分類號 | 415.74 |
關鍵詞 | 多核細胞血管組織球瘤; 丘疹; Multinucleate cell angiohistiocytoma; |
語 文 | 英文(English) |
中文摘要 | 多核細胞血管組織球瘤是一種少見的皮膚病灶。臨床上的特徵是通常在中年女性的四肢上有多顆的丘疹。我們報告一位42歲的女性,在一年內,她的額頭上出現一個逐漸擴大的紫色班塊及些許個棕色至紫紅色的丘疹。皮膚切片下,可以看到在眞皮層有血管的增生,周遭的結締組織中有不等數目,大且奇異的多核細胞。免疫組織化學染色顯示,內皮細胞對CD34呈陽性反應,多核細胞只對vimentin呈陽性反應,細胞間隙中的單核細胞對CD68呈陽性反應,因此,我們的診斷是多核細胞血管組織球瘤。我們報告這個病例,並且回顧相關的文獻。 |
英文摘要 | Multinucleate cell angiohistiocytoma (MCAH) is a rare skin lesion characterized by multiple papules, usually found on the extremities of middle-aged women. We report such a case in a 42-year- old woman who had noticed a gradually enlarging purpuric plaque and several brown-to-violet papules on her forehead for one year. A biopsy specimen of the plaque showed dermal vascular proliferation embedded in connective tissue containing a number of bizarre, multinucleated giant cells. Immunohistochemical study showed that the endothelial cells were positive for CD34, the multinucleate cells were positive only for vimentin, and the mononuclear interstitial cells were positive for CD68. A diagnosis of multinucleate cell angiohistiocytoma was made. We report this case and review the literature. |
本系統中英文摘要資訊取自各篇刊載內容。