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題名 | The Probability of Blindness in Patients Treated for Glaucoma=治療過後的青光眼仍會失明的機率 |
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作 者 | 張立群; 鄧美琴; 張學文; 賴盈州; 林蓓文; 蔡振嘉; | 書刊名 | 長庚醫學 |
卷期 | 28:7 2005.07[民94.07] |
頁次 | 頁492-497 |
分類號 | 416.748 |
關鍵詞 | 青光眼; 失明; 眼壓; Glaucoma; Blindness; Intraocular pressure; |
語文 | 英文(English) |
中文摘要 | 背景:找出經過治療過後的青光眼仍會失明的可能性及可能導致失明的原因。 方法:回顧分析於2003一整年內於高雄長庚眼科接受青光眼治療2年以上的病歷。 結果:186名患者的病歷被分析,其中66名患者於初次到本院眼科時即因青光眼而導致失明。172名患者經過平均10.6±4.67年的追蹤,期間有27人/31隻眼精因青光眼導致失明。Kaplan-Meier計算出於16年的治療後,有28.6%的機會導致一眼以上失明。初診時視野缺損較大的、年紀較長的、順從性不佳的比較容易導致失明。而性別、青光眼的類別、和初診時單眼是否失明、是否有糖尿病高血壓則和導致失明較無關係。 結論:青光眼即使經過治療仍有相當可能性會進展到失明的階段,而年紀較長、初診時視野較差者、順從性較差者則較容易進展到失明。 |
英文摘要 | Background: To investigate the risk factors and problability of blindness in patients treated for glaucoma. Methods: The study design was a retrospective, hospital-based, clinical chart, review study. Medical records were reviewed from patients seen between January 2003 and December 2003 at the Kaoshiung Chang Gung Memorial Hospital eye clinic, who had been diagnosed with glaucoma in 1986 or later and who had been treated for at least 2years for glaucoma. Results: A total of 186 charts were reviewed, which included 66 patients who were blind in at least one eye from glaucoma on presentation. A total of 172 patients and 290 eyes were followed-up for a mean duration of 10.6±4.67 years. Twenty seven patients and 31 eyes developed blindness from glaucoma during follow-up. The Kaplan-Meier survival estimate at 16 years was 28.6% for glaucoma-related blindness in at least one eye. A worse visual field on presentation, older age, and poor compliance during therapy were significantly associated with the developemtn of blindness. Glaucoma type, a gender difference, systemic disease, greater intraocular pressure fluctuation in the last year of therapy and blindness in one eye on presentation did not show a signficiant relationship with the rate of development of blindness. Conclusion: Blindness from treated glaucoma is considerable. Our results gave a 28.6% probability of blindness at 16 years in at least one eye. An older age, poor compliance and a worse visual field on presentation were significant risk factors. |
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