查詢結果分析
來源資料
頁籤選單縮合
題 名 | Deceased-Donor Liver Transplantation: 10 Years' Experience at Change Gung Memorial Hospital-Kaohsiung Medical Center=屍肝移植在高雄長庚醫院的十年經驗之回顧 |
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作 者 | 楊志權; 陳耀森; 王世和; 林志哲; 劉柏屏; 劉約維; 楊景翔; 洪國禎; 江原正; 林燦勳; 鄭汝汾; 黃棟樑; 姚文聲; 邢福柳; 陳肇隆; 王植熙; | 書刊名 | 長庚醫學 |
卷 期 | 28:3 2005.03[民94.03] |
頁 次 | 頁133-141 |
分類號 | 416.246 |
關鍵詞 | 屍肝移植; 同位肝臟移植; Deceased-donor liver transplantation; Orthotopic liver transplantation; |
語 文 | 英文(English) |
中文摘要 | Background: The purpose of this study was to summarize the outcomes we achieved using deceased-donor liver transplantation (DDLT) in the past 10 years at Chang Gung Memorial Hospital-Kaohsiung Medical Center (CGMH-KMC). Methods: Between March 1993 and March 2003, 53 DDLTs were performed at CGMH-KMC. Patients were divided into 2 stages: stage 1 (n= 22) from March 1993 to February 1998, and stage 2 (n = 31) from March 1998 to March 2003. Indications for transplantation, patient demographics, surgical procedures, and long-term outcomes were reviewed. Results: Indications for transplantation were biliary atresia (16), post-hepatitis B/C viral cirrhosis with or without hepatocellular carcinoma (21), Wilson’s disease (8), primary biliary cirrhosis (3), and miscellaneous (5). Two retransplants were carried out for secondary biliary cirrhosis using primary livedonor liver transplantation (LDLT). Ten patients received grafts from 6 splitliver transplantations. Over-all Kaplan-Meier 1-, 3-, and 5-year survival rates were 88.46%, 83.86%, and 79.87%, respectively. A significant improvement in patient survival was observed in stage 2. The Kaplan-Meier 1- and 5-year patient survival rates in stage 2 were 96.67% and 92.95%, respectively. Fifteen patients developed vascular complications. Nine patients died in this series for an overall mortality rate of 17%. Conclusions: Deceased-donor liver transplantation is well established as the treatment of choice for acute and chronic liver failure in Taiwan. Satisfactory outcomes have been attained in those transplanted to date. |
英文摘要 | 背景:本文概述過去十年屍肝移植在高雄長庚醫院的經驗。 方法:自1993年3月至2003年3月共10年,高雄長庚醫院一共完成53例屍肝移植。共分為兩個時期,第一期 (n=22)自1993年3月至1998年2月。第二期(n=31)自1998年3月至2003年3月。本文回顧肝臟移植的適應症,手術步驟及長期追蹤病人的結果。 結果:移植的適應症,包括膽道閉鎖(16)、B或C型肝炎合併有無肝癌(23),威爾森氏症候(8),原發性膽道肝硬化(3)及兩例活體肝臟移植後,次發性膽道肝硬化接受再次的肝移植(2)和其他(5)。53例病人存活率,在1年、3年及5年各為88.46%、83.86%及79.87%。第二期病人存活率有顯著的進步,在1年及5年各為96.67%及92.95%。共有15名發生血管併發症,到目前有9名病患死亡。 結論:肝臟移植在台灣已經成為一種成熟的技術,來治療急性和慢性肝衰竭的病人,並獲至良好的成果。 |
本系統中英文摘要資訊取自各篇刊載內容。