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| 題 名 | Paranasal Sinus Involvement in Acute Lymphoblastic Leukemia=急性淋巴芽細胞白血病於副鼻竇腔的進犯 |
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| 作 者 | 張伯宏; 陳盈霖; 李達人; 李立昂; 廖順奎; | 書刊名 | 長庚醫學 |
| 卷 期 | 27:12 2004.12[民93.12] |
| 頁 次 | 頁924-929 |
| 分類號 | 415.635 |
| 關鍵詞 | 急性淋巴芽細胞白血病; 副鼻竇腔; 內視鏡鼻竇手術; Acute lymphoblastic leukemia; Paranasal sinus; Endoscopic sinus surgery; |
| 語 文 | 英文(English) |
| 中文摘要 | 急性淋巴芽細胞白血病是骨髓造血之惡性疾病,但在罕見的情況下,會進犯至鼻及鼻竇腔區域。此外,副鼻竇腔的進犯可能導致鼻竇炎及眼窩之併發症而需要更積極的治療。此病例為26歲男性病人,有罹患急性淋巴芽細胞白血病及一次復發的病史。病人發生進展快速的眼窩周圍疼痛及眼球突出等常見於鼻竇炎眼窩併發症的症狀,鼻竇電腦斷層檢查發現右側上頷竇及篩竇混濁性病灶合併眼窩骨破壞。經緊急內視鏡鼻竇手術施行眼窩減壓及組織切片檢查,病理報告顯示呼吸黏膜淋巴芽細胞浸潤,骨髓細胞學檢查證實急性淋巴芽細胞白血病第二次復發的診斷。急性淋巴芽細胞白血病病人之鼻竇炎需探查可能的阻塞原因,而內視鏡鼻竇手術可以提供組織病理學診斷,治療鼻竇炎及眼部併發症。 |
| 英文摘要 | Acute lymphoblastic leukemia (ALL) is a hemopoietic malignancy of the bone marrow that rarely invades the sinoasal area. If infiltration of paranasal sinuses occurs, it may lead to rhinosinusities and orbital complications that need aggressive treatment. In this report, a 26-year-old male patient who had a history of ALL and had one relapse, suffered from rapid progression of right periorbital pain and exophthalmos, which usually presented in patients with orbital complications of sinusities. A sinus computed tomography showed right maxillary and ethmoid sinus opacification with orbital bone destruction. Urgent endoscopic sinus surgery (ESS) was performed for orbital decompression and histopathologic diagnosis. Pathology revealed lymphoblast infiltration and inflammation of respiratory mucosa. Subsequent bone marrow aspiration cytology confirmed the diagnosis of a second relapse of ALL. Obstructive causes of sinusities should be evaluated in patients with ALL. ESS has proven to be effective in obtaining tissue for histopathologic diagnosis, and in treating patients with sinusities with orbital complications. |
本系統中英文摘要資訊取自各篇刊載內容。