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頁籤選單縮合
| 題 名 | Impact of Initial Antibiotic Choice on Clinical Outcomes of Community-Acquired Pneumonia in Adults=經驗性抗生素的選擇對成人社區型肺炎臨床結果之影響 |
|---|---|
| 作 者 | 林泰綜; 郭英調; 吳綺華; 吳杰亮; 金佩玲; 許正園; | 書刊名 | 胸腔醫學 |
| 卷 期 | 19:6 2004.12[民93.12] |
| 頁 次 | 頁436-444 |
| 分類號 | 418.281 |
| 關鍵詞 | 社區型肺炎; 抗生素; 花費效益; Community-acquired pneumonia; Antibiotic; Cost-effectiveness; |
| 語 文 | 英文(English) |
| 中文摘要 | 前言:足夠與立即的經驗性抗生素治療可改善社區型肺炎的臨床結果。於中央健保局對抗生素使用的規範下,我們有興趣瞭解經驗性抗生素的選擇對社區型肺炎臨床結果之影響。 方法:我們回溯性地納入於西元2002年一年中住院於臺中榮民總醫院之輕度到中度(Fine risk class II, III and IV)社區型肺炎的病患。我們以住院總費用、住院天數及在院存活率(in-hospital survival rate)為評估臨床結果的參數去比較使用第一線抗生素與第二線抗生素者之間的臨床結果。 結果:總共一百一十六社區性肺炎病患收案。與使用第一線抗生素群比較後發現使用第二線抗生素群有較長之住院天數(Mann-Whitney U test, p=0.008)與較高之住院總費用(Mann-Whitney U test, p=0.0004),但是存活率無差別(log-rank test; p=0.662)。 結論:使用第二線抗生素的患者無法證實有較佳的臨床結果,這可能導因於二組間疾病嚴重度的差異。 |
| 英文摘要 | Background: Adequate and immediate empiric antibiotic treatment improves the outcome of community-acquired pneumonia (CAP). Using the antibiotic regulation guidelines of the Bureau of National Health Insurance, we examined the impact of initial antibiotic choice on the outcome of CAP. Methods and patients: In this study, we retrospectively reviewed patients with CAP (modified Fine risk classes II, III and IV) who were hospitalized in Taichung Veterans General Hospital in 2002. We assessed the outcome parameters, including total hospital costs, length of hospital stay (LOS), and in-hospital survival rate. We compared the outcome parameters of 2 groups: the 1st line antibiotics (1st ATB) group and the 2nd line antibiotics (2nd ATB) group. Results: A total of 116 patients were enrolled in the study. Compared to the 1st ATB group, the 2nd ATB group had a longer length of stay (Mann-Whitney U test, p=0.008) and higher hospital costs (Mann-Whitney U test, p=0.0004), but no significant difference in survival rate (log-rank test, p=0.662). |
本系統中英文摘要資訊取自各篇刊載內容。