頁籤選單縮合
| 題 名 | Prolonged Hypoglycemia in Full-term, Small for Gestational Age Newborns=足月低體重新生兒之持續性低血糖 |
|---|---|
| 作 者 | 戴熒黛; 林毓志; 林其和; | 書刊名 | Clinical Neonatology |
| 卷 期 | 11:1 2004.06[民93.06] |
| 頁 次 | 頁19-23 |
| 分類號 | 417.517 |
| 關鍵詞 | 足月低體重新生兒; 持續性低血糖; Prolonged hypoglycemia; SGA; Newborn; |
| 語 文 | 英文(English) |
| 英文摘要 | Objectives: To investigate the course of prolonged hypoglycemia in full-term, small for gestational age (SGA) newborns and their neurologic outcomes. Materials and Methods: We retrospectively reviewed the medical records of full-term SGA newborns born in National Cheng Kung University Hospital between November 1, 1991 and December 31, 2001. They were routinely screened for hypoglycemia at the ages of 1, 2, 4, 6, 12, 24, and 48 hours by dextrostix testing. Hypoglycemia was defined as a glucose value lower than 35 mg/dL within 3 hours, lower than 40 mg/dL between 3 and 24 hours, and lower than 45 mg/dL at more than 24 hours of age. Serum cortisol and insulin levels were determined when the duration of hypoglycemia was exceeded 7 days. Data on risk factors and neurologic outcomes were collected and analyzed. Results: Thirty- five full-term SGA newborns developed hypoglycemia after birth. Eight (23%) of them had hypoglycemia for longer than 48 hours and recovered within 7 days of age; 8 (23%) patients had hypoglycemia for longer than 7 days. The majority recovered from hypoglycemia after glucose intake or a parenteral glucose infusion. However, 4 patients eventually required steroid or glucagon therapy. Their serum insulin and cortisol levels were within normal ranges. Five of the 8 patients with prolonged hypoglycemia developed neurologic dysfunction. Conclusions: Prolonged hypoglycemia in full-term SGA newborns is not uncommon. The majority of hypoglycemic episodes were transient. However, those with prolonged hypoglycemia were at risk of developing neurodevelopmental disorders, and thus aggressive management was indicated. |
本系統中英文摘要資訊取自各篇刊載內容。