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題 名 | 海藻素材創傷敷材之研究=Alginate Hydrogel Dressing in Wound Healing |
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作 者 | 林維新; | 書刊名 | 紡織中心期刊 |
卷 期 | 14:1 2004.01[民93.01] |
頁 次 | 頁22-33 |
分類號 | 478.16 |
關鍵詞 | 海藻酸; 水膠; 敷料; Alginate; Hydrogel; Wound dressing; |
語 文 | 中文(Chinese) |
中文摘要 | 當皮膚有較大的傷口時,必須將醫用敷料覆蓋在傷口上,以抑制傷口細菌數量、減少水分蒸發及蛋白質喪失、減輕疼痛、保護傷口、避免重要組織如神經、血管、骨骼壞死。所以醫用敷料應具有抑制傷口細菌數量、減少水分蒸發及蛋白質喪失、減輕疼痛、保護傷口等功能。而以天然高分子所製成的醫用敷料是被認為最具又潛力的。海藻酸鈉由天然褐藻中所萃取出為一天然高分子具有生物相容性及生物可分解性。利用其材料之特性形成海藻酸水膠。由於能保持傷口濕潤使其能加速傷口之癒合。 紡織中心所製造之敷材進行數材細胞毒性測試及動物貼附試驗,由實驗結果中得知,敷材不具有細胞毒性並能促進傷口癒合能力,且敷材引起生理上之發炎反應性低,適合作為燙傷敷材。在體外細胞毒性實驗中敷材並無細胞毒性;在動物實驗結果中,以傷口的修復程度來比較,其在手術後21天,敷料所覆蓋的傷口組織之修復程度已經接近復原的程度。 |
英文摘要 | For centuries it has been considered that wound has to be kept dry in order to create an ideal environment to heal. In recent years the moist healing concept has been established and a new generation of wound dressing has been developed to provide a moist healing environment consequently reduce healing time. Alginate wound dressing has a unique natural ability to assist in healing process. Alginate wound dressing could keep wound moist and provide an ideal healing environment. Because dressing doesn't adhere to the wound, pain is consequently reduced while the dressing is placed or removed. |
本系統中英文摘要資訊取自各篇刊載內容。