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頁籤選單縮合
題名 | 長時間運動對大學男生周邊血液中B細胞數量與B細胞增殖功能之影響=Impacts on B Cell Count and B Cell Proliferation in Peripheral Blood of Male College Students after an Acute Prolonged Exercise |
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作者 | 黃森芳; | 書刊名 | 大專體育學刊 |
卷期 | 6:2 2004.06[民93.06] |
頁次 | 頁271-283 |
分類號 | 528.9012 |
關鍵詞 | B細胞; 增殖功能; 馬拉松; 長時間運動; B cell; Proliferation; Prolonged exercise; Marathon race; |
語文 | 中文(Chinese) |
中文摘要 | 規律適度運動促進免疫功能,長時間耗竭式的運動則會引起運動後免疫抑制現象。研究目的:一般大學男生42.195公里跑步前後,周邊血液中B細胞數量與增殖功能改變情形。本研究以14位大學男生為受試者,平均年齡21.82±l.l6歲、身高173.75±3.90 公分、體重70.19±4.12公斤、最大耗氧能力43.24± 2.05,平均以5.43± 0.31完成42.195 公里馬拉松跑步運動,血液樣本於跑前30分及跑後0分、12時、24時、36時與48時,於受試者前手臂抽取,血液樣本加入以螢光標記之各顯免疫細胞特殊抗原單株抗體,以流式細胞計數儀計算B細胞數量;以LPS刺激淋巴細胞,評估B細胞增殖功能。結果:一般大學男生完成42.195公里跑步後,周邊血液中B細胞數量與增殖功能24小時內顯著低於跑步前。結論:一般大學男生42.195公里馬拉松跑步後,周邊血液中B細胞數量與增殖功能至少降低24小時,對整體免疫功能可能影響不大,但進行類似活動後,仍應注意身體保健。 |
英文摘要 | Regular moderate exercise enhances immune function; while prolonged exhaustive exercise induces post-exercise immunosuppression. The purpose of this study was to investigate the differences of B cell count and proliferation in peripheral blood of male college students between, before and after a 42.195km race. The subjects were 14 male college students, and their averaged age was 21.82± 1.18 years, height 173.76± 3.90cm, weight 70.19 ±4.12kg,body fat 17.59± 2.33%, VO2max 43.24± 2.05ml/kg/min, and the averaged time for completing the 42.195km running were 5.43± 0.31 hours. The blood samples were drawn at 30 minutes before and 0 minute, 12 hours, 36 hours, 48 hours after the race from subjects' forearm veins. Blood samples were conjugated with the labeled cloned antibodies of the specific immune cell surface antigens, and the B cell count was analyzed using the flow cytometer; LPS was used for assessing B cell proliferation. Results indicated both the B cell count and the proliferation were decreased or suppressed at least for 24 hours in peripheral blood of subjects after the race. In conclusion, the number and proliferation of B cells were decreased or suppressed at least for 24 hours in peripheral blood of male college students after a 42.195km running. Even though the impacts on the whole immune function is limited, the exercisers should still take good care of their health after completing such exercise. |
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