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題 名 | Clear Cell and Non-clear Cell Hepatocellular Carcinoma: A Case Report and Literature Review=清細胞及非清細胞肝癌--病例報告 |
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作 者 | 劉振華; 蔡慧玲; 徐首民; 胡東和; 陳賜生; | 書刊名 | The Kaohsiung Journal of Medical Sciences |
卷 期 | 20:2 2004.02[民93.02] |
頁 次 | 頁78-82 |
分類號 | 416.246 |
關鍵詞 | 清細胞肝癌; 高迴音; 低迴音; Clear cell hepatocellular carcinoma; Hyperechoic; Hypoechoic; |
語 文 | 英文(English) |
中文摘要 | 清細胞肝癌是少見的一種肝癌變異體,內含大量脂肪及肝醣,其曾被認為預後較好,但近年來則仍有爭議性。基因研究認為, diploid 及 non-diploid 基因引導細胞分化,與肝癌預後較有關係。清細胞肝癌可分為局部與瀰漫型,而本病例含有二顆結節,分別為清細胞與非清細胞肝癌,則甚少見。本案例為 61 歲男性,肝臟右葉含二個相鄰的高迴音與低迴音結節。甲-胎兒蛋白 6,370 ng/mL,曾接受肝臟右葉第八節切除術。經病理證實分別為清細胞肝癌(高迴音)與非清細胞肝癌(低迴音)。在肝臟完全切除後,仍發生左肩骨轉移,並接受放射治療。由本例得知,合併清細胞與非清細胞肝癌,雖已完全切除腫瘤,仍須密切觀察。 |
英文摘要 | Clear cell hepatocellular carcinoma (HCC) is an uncommon variant of HCC. It is considered to have a better prognosis than non-clear cell HCC, but recent large studies show that there is some controversy. DNA image cytometry reveals diploid and non-diploid DNA content tumors that have different pleomorphisms and mitosis corresponding to different prognoses. Clear cell HCC is classified as focal or diffuse. Herein, we report a rare case of a 61-year-old male with two adjacent hyper- and hypoechoic hepatic nodules and an alpha-fetoprotein concentration of 6,370 ng/mL. Pathologic examination of a specimen obtained during wedge hepatectomy showed both clear cell and non-clear cell HCC. Bone metastasis was later found. We suggest that a patient with clear cell HCC should be followed up closely after complete resection. |
本系統中英文摘要資訊取自各篇刊載內容。