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題名 | Uterine Leiomyosarcoma Metastatic to the Scalp--A Case Report and Review of the Literature=子宮平滑肌肉瘤轉移至頭皮--病例報告暨文獻回顧 |
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作者 | 王淳樺; 陳國熏; 蕭惠樺; 楊曉芳; | 書刊名 | 中華皮膚科醫學雜誌 |
卷期 | 22:1 2004.03[民93.03] |
頁次 | 頁69-73 |
分類號 | 415.789 |
關鍵詞 | 子宮平滑肌肉瘤; 頭皮; Leiomyosarcoma; Scalp metastases; |
語文 | 英文(English) |
中文摘要 | 平滑肌肉瘤是一個罕見腫瘤,較常出現於子宮、後腹壁腔、胃壁或大血管壁中;轉移至皮膚的個案更是罕見。在此吾人提出一個由子宮平滑肌肉瘤轉移至遠處頭皮的病例報告。該病例經由組織病理及免疫組織化學的檢查(包括desmin和smooth muscle actin的陽性反應;cytokeratin,S-100和CD117的陰性反應)確定診斷。肉瘤之遠處皮膚轉移多表示病症末期且癒後不佳,但是該病人在肉瘤遠處皮膚轉移後接受化學治療及規則門診追蹤而繼續存活,距離其頭皮腫塊出現已達21個月。 |
英文摘要 | Leiomyosarcoma is an uncommon neoplasm. It occurs more frequently in the uterus, retroperitoneal space, stomach and large vessels. Metastatic leiomyosarcomas to the skin, in general, are extremely rare. Herein, we describe a patient with leiomyosarcomas of uterus who developed multiple cutaneous metastatic leiomyosarcomas on the scalp over the duration of one year. The diagnosis was confirmed by histopathological and immunohistochemical studies, which showed the tumor positively stained for desmin and smooth muscle actin, while negatively stained for cytokeratin, S-100 and CD117 (c-kit). Distant cutaneous metastases from sarcoma usually occur as a late event and carry a poor prognosis. The course in our patient is somewhat unusual, and she is still alive now, which is about 21 months after the occurrence of skin metastasis. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。