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題名 | 氣喘的替代性藥物治療=Alternative Pharmacotherapy of Bronchial Asthma |
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作 者 | 許峻榮; | 書刊名 | 北市醫學雜誌 |
卷期 | 1:1 2004.01[民93.01] |
頁次 | 頁25-31 |
分類號 | 415.425 |
關鍵詞 | 氣喘治療; 金製劑; 免疫球蛋白; 環孢靈; 肝素; Asthma therapy; Gold; IVIG; Cyclosporine; Heparin; Methotrexate; Troleandomycin; Furosemide; |
語文 | 中文(Chinese) |
中文摘要 | 背景:氣喘被定義為氣道發炎和可逆性的氣道阻塞,氣道過度反應,標準治療是根據1999年的National Heart,Lung,Blood Institute訂定的治療準則,但是仍然有少數病患,使用上述藥物達極限仍未改善症狀,並且大量使用類固醇恐怕引起副作用。方法:本文是各家研究報告,探討非類固醇的氣喘替代療法與成效。包含methotrexate、金製劑(gold)、免疫球蛋白(IVIG)、環孢靈(cyclosporine)、肝素(heparin)、troleandomycin和furosemide。結論:這些研究報告,目前臨床試驗較完整,可信度較高,可低類固醇劑量及副作用,只有MIX與金製劑。其他的藥劑因報告數量少,仍有研究發展空間。 |
英文摘要 | Bronchial asthma is a disease that is characterized by airway inflammation, reversible airway obstruction and pulmonary symptoms. Many clinicians consider the use of alternative agent in treating asthma patients whose disease remained poorly controlled while received standard therapy. The alternative agents, included methotrexate, gold, IVIG, cyclosporine, heparin, troleandomycin and furosemide, have been evaluate in prospective randomized trials. Methotrexate and gold appear to be the most promising in terms of steroid-sparign and side effect profiles. Other agents in current studies lack of significant potential steroid-sparing effect in the long term treatment of steroid dependence asthma. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。