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| 題 名 | Epidemiological and Clinical Features of Group A Streptococcus Pharyngitis in Children=兒童A族鏈球菌咽喉炎流行病學與臨床表徵之研究 |
|---|---|
| 作 者 | 林孟勳; 張碧峰; 馮文侃; 顏志瑋; 洪焜隆; 林淑菁; | 書刊名 | 臺灣兒科醫學會雜誌 |
| 卷 期 | 44:5 民92.09-10 |
| 頁 次 | 頁274-278+318 |
| 分類號 | 417.5333 |
| 關鍵詞 | A族鏈球菌; 咽喉炎; Group A streptococcus; Pharyngitis; |
| 語 文 | 英文(English) |
| 中文摘要 | 為了瞭解兒童A族鏈球菌咽喉炎的流行病學,我們做了此前瞻性的研究。自2001年1月1日至2002年12月31日間,凡在國泰內湖分院小兒科門診,因為急性咽喉炎接受喉頭抹片細菌培養的病童皆列入研究。所有病例均紀錄年齡、性別、發病季節及臨床症狀,并以統計方式針對感染A族鏈球菌咽喉炎的病例與非A族鏈球菌咽喉炎的病例加以分析比較。在兩年的時間中,我們總共收集了1175例喉頭抹片檢體,其中分離出A族鏈球菌252例,約估了21.4%。男孩有較高的比例罹患A族鏈球菌咽喉炎。這些A族鏈球菌咽培養陽性的病童其年齡初為7.8±2.3歲。而年齡介於6到11歲間的兒童較容易罹患A族鏈球菌咽喉炎。另外在每年三月至五月及十月至十二月間,病童喉頭抹片有較高之比例分離出A族鏈球菌。雖然統計顯示某些臨床症狀和A族鏈球菌咽喉感染有獨立之相關性:例如出現喉嚨痛、扁桃腺肥大、前頸部淋巴腺朣大、猩紅熱樣皮疹及沒有流鼻水等會增加感染A族鏈球菌咽喉炎的可能性;但是具有道些臨床表徵的病童其A族鏈球菌咽培養陽性的比例卻不到一半。因此本研究顯示,兒童感染A族鏈球菌咽喉炎在內湖地區并非不常見。其罹病率和病童性別、年齡及季節有關。單獨靠臨床症狀來診斷兒童A族鏈球菌咽喉炎是不可靠的。 |
| 英文摘要 | In order to understand the prevalence of childhood streptococcal pharyngitis, isolation of group A Streptococcus (GAS) was attempted from throat swabs of pharyngitis patients. Children aged between 1 and 15 years presenting to the outpatient department with pharyngeal erythema were prospectively enrolled in the study. Demographic data and presenting symptoms and signs for each patient were recorded and a throat swab was taken. Of 1175 throat cultures obtained, GAS was isolated in 252 cases (21.4%). Of these, 142 (56.3%) were boys and 110 (43.7%) girls. A higher proportion of boys was found with GAS pharyngitis (1.29:1). The mean age of GAS culture-positive patients was 7.8±2.3 years old. Patients aged between 6 and 11 years were more prevalent in GAS pharyngitis. Ninety (35.7%) of our GAS pharyngitis patients occurred between March and May. A second smaller peak occurred between October and December. The following factors showed independent positive correlation with GAS infection: sore throat (p<0.001), no coryza (p=0.011), tonsillar swelling (p<0.001), anterior cervical adenopathy (p=0.029) and scarlatiniform rash (p<0.001). However, GAS was found in less than half of the patients who had these clinical manifestations. In conclusion, pharyngeal infection with GAS in children is not uncommon. The prevalence of GAS pharyngitis is related to patient gender, age, and month of the year. Diagnosis of GAS pharyngitis based on clinical features alone is unreliable. |
本系統中英文摘要資訊取自各篇刊載內容。