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題名 | Ovarian Endometrioma Associated with Very High Serum CA-125 Levels=卵巢子宮內膜異位瘤合併異常上升血清CA-125指數 |
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作者 | 蕭啟信; 張明揚; 江其鑫; 謝景璋; 謝燦堂; | 書刊名 | 長庚醫學 |
卷期 | 26:9 2003.09[民92.09] |
頁次 | 頁695-699 |
分類號 | 417.27 |
關鍵詞 | 卵巢子宮內膜異位瘤; 血清CA-125濃度; Endometrioma; CA-125; |
語文 | 英文(English) |
中文摘要 | CA-125是一種細胞表面的醣蛋白,它在非黏液性上皮性卵巢癌的個案中,百分之八十可見上升的情形;而在一般正常人血清中CA-125濃度通常是小於35。血清中CA-125濃度的上升在幾種良性的婦科病灶中也可見到,例如骨盆腔發炎、子宮肌瘤、子宮肌腺瘤、妊娠、自然流產,尤其以子宮內膜異位症曘為常見。然而,子宮內膜異位症患者血液中CA-125濃度很少上升超過100 IU/mL。在本篇文章中報告案例為單側卵巢子宮內膜異位瘤合併異常升高之血清CA-125濃度(>6000 IU/mL),在病患接受卵巢內膜異位瘤切除後,血清CA-125濃度?回復為正常。本案例的報導說明了刀使在婦科方面的良性疾病也有可能合併極度異常上升的CA-125濃度,併討論此類極度異常上升CA-125濃度的可能解釋。 |
英文摘要 | CA-125 is a 220-kD cell surface glycoprotein present in over 80% of non-mucinous epithelial ovarian carcinomas and it occurs in the serum of healthy males and females at lo concentrations (<35 U/mL). Serum CA-125 concentration may also be moderately elevated in several benign conditions, such as pelvic inflammatory disease, uterine fibroids, pregnancy, spontaneous abortion with chromosomal abnormality, and especially in endometriosis. However, serum CA-125 concentration is seldom >100 IU/ml in endometriosis. In this paper, we present a patient with unilateral ovarian endomenteioma associated with abnormally high serum CA-125 level (>6000 U/ml) and after excision of the ovarian tumor, the CA-125 levels returned to normal. Our case further emphasizes the association of high levels of CA-125 with benign gynecologic conditions and we discussed the possible explanations for this abnormal elevation of CA-125 levels. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。