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題名 | Nash Equilibrium on Induction of Bacteriophage λ-Escherichia coli Impasse=噬菌體λ-大腸桿菌誘導僵局之「納許均衡」 |
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作者 | 陳博彥; | 書刊名 | Journal of the Chinese Institute of Chemical Engineers |
卷期 | 34:3 2003.05[民92.05] |
頁次 | 頁311-318 |
分類號 | 460.02 |
關鍵詞 | 賽局理論; 噬菌體λ; 納許均衡; 溫度誘導; Bacteriophage λ; Temperature induction; Game theory; Subgame perfect Nash equilibrium; Virulence reduction; |
語文 | 英文(English) |
中文摘要 | 根據動態而非靜態賽局所演化之「納許均衡」顯示,λ之「減毒作用」及大腸桿菌之「技巧改進」為「溫度誘導」過程「宿主─寄生蟲」演化之合理表現。因「納許均衡」而演化出之「合作結局」乃基於物種共存永續經營之考量。宿主經由其「技巧改進」來訴求一無λ存在之環境以利正常生長;同時,λ選擇探用較低毒性策略以維持宿主生存活性以利其自身之存活。λ之「減毒」作用增強此二元物種之共存,因此得到緩和誘導之基因表達結果。此策略性賽局顯然澄清闡述先前研究之假設結果。 |
英文摘要 | Based on the Nash equilibrium evolving in an extensive-form, not a normal-form game, it is found that virulence reduction of λ and skill improvement of E. coli is a reasonable outcome of direct temperature induction of bacteriophage λQ¯-mutant in Escherichia coli. This cooperative situation evolved as the Nash equilibrium is basically considered as a long-term sustainable development strategy for species coexistence. A host demands a λ-free environment by skill improvement for normal growth. Meanwhile, λ chooses a less virulent strategy to maintain host viability for the sake of its survival. Virulence reduction of λ enhances the coexistence of λ and E. coli; thus, moderate induction results. This strategic game obviously clarifies certain hypothesized results shown in previous works. |
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