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題 名 | Predictors of Esophageal Stricture in Children with Unintentional Ingestion of Caustic Agents=兒童意外吞食腐蝕性物質造成食道傷害的預測因子 |
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作 者 | 陳宗義; 高常發; 莊錦豪; 郭馨蔚; 刁茂盟; | 書刊名 | 長庚醫學 |
卷 期 | 26:4 2003.04[民92.04] |
頁 次 | 頁233-239 |
分類號 | 415.51 |
關鍵詞 | 白血球; C反應蛋白; 腐蝕性; 食道; 狹窄; Leukocyte; C-reactive protein; Caustic; Esophagus; Stricture; |
語 文 | 英文(English) |
中文摘要 | 背景:臆測吞食腐蝕性物質成食道傷害的嚴重度對於臨床醫師是一個挑戰性的問題。本研究影響的在探討吞食腐蝕性物質的兒童其臨床表與預後的相關性。 方法:本研究包含了32個食入腐蝕性物質造成食道傷害的兒童。這些病人的徵兆,症狀,白血球數以及C反應蛋白皆有記錄。 結果:病人有三種以上之徵兆和症狀者有較為嚴重的食道傷害及狹窄。嚴重食道受傷的病人比低度受傷的病人有較多的徵兆及症狀。嚴重受傷的病人顯然較為容易日後發生食道狹窄。食入腐蝕性物質的酸鹼與食道狹窄有關,而與食道受傷程度無關。白血球數與食道受傷嚴重度統計上無顯著差異。在有食道狹窄病人的白血球數平均值接近於無食道狹窄病人的白血球平均值。C反應蛋白在兩組病人之間統計上亦無顯著差界 結果:基於以上的資料,對於預測食道腐蝕性傷害後,食道受傷及嚴重度而言,白血球及C反應蛋白不是有用的指標。吞食鹼性物質批酸性物質更可能發生食道狹窄。吞食腐蝕性物質後,愈多的徵兆需要愈積極的處置。 |
英文摘要 | Backgorund: Predicition of the severity of esophageal injury following ingestion of a caustic substance is a challenging problem for clinicians. It was hoped that risk factors for the early prediction of esophageal stricture in such patents could be identified in this study. Methods: This study comprises an evaluation of 32 children with esophageal injury due to ingestion of caustic materials. Patients’ signs and symptoms as well as laboratory data including leukocyte counts and C-reactive protein level were reviewed. Results: Patients who presented with a greater number of symptoms and signs were inclined to have more severe esophageal injury and stricture. The frequency of symptoms and signs in patients with serious esophageal injury was higher than that in patients with low-grade injury. Patients with severe injury were more significantly associated with the occurrence of stricture. The characteristic of caustic ingestion was associated with esophageal stricture, but not esophageal injury. There was no statistically significant difference in leukocyte counts relative to severity of esophageal injury. The mean of leukocyte counts of patients with esophageal stricture was close to that of patients with out esophageal stricture. There was also no statistically significant difference in C-reactive protein values between the 2 groups of patients. Conclusions: Leukocyte counts and C-reactive protein are not useful parameters for predicting the severity of esophageal injury and occurrence of stricture following injury to the esophagus by caustic materials. Alkali ingestion more probable leads to esophageal stricture than acid ingestion. After caustic ingestion, the presence of a greater number of symptoms and signs suggests a more severe injury, which necessitates more-aggressive management. |
本系統中英文摘要資訊取自各篇刊載內容。