頁籤選單縮合
題名 | Primary Intraspinal Mesenchymal Chondrosarcoma: A Case Report and Literature Review=原發性脊椎內間質軟骨肉瘤--病例報告及文獻回顧 |
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作者 | 黃國烽; 昝文清; 林進耀; | 書刊名 | 長庚醫學 |
卷期 | 26:5 2003.05[民92.05] |
頁次 | 頁370-376 |
分類號 | 416.66 |
關鍵詞 | 間質軟骨肉瘤; 原發性脊椎內腫瘤; Mesenchymal chondrosarcoma; Primary intraspinal tumor; |
語文 | 英文(English) |
中文摘要 | 間質軟骨肉瘤是一種相當少見的骨骼與軟組織的惡性腫瘤。在骨骼架構以外的間質軟骨肉瘤特別是發生在中樞神經系統是更少見。大部份在中樞神經的間質軟骨肉瘤也以在顱內居多,間質軟骨肉瘤發生在脊椎只有少數的病例報告。原發性脊椎內間質軟骨肉瘤治療經驗是非常的有限。我們報告一例21歲的男性有背痛與進行性的兩下肢無力與麻木。T1核磁共振影像呈現出在T8的部位有低強度的腫瘤。這個腫瘤是由後方手術並完全切除。顯微鏡檢查與免疫組織生化研究確定其診斷是間質軟骨肉瘤。脊椎放射線治療與化學治療也同時給予以預防局部的復發與轉移。這個病患在手術之後一年的追蹤中完全沒有症狀。在此,我們也回顧了目前的文獻報告過的22例原發性脊椎內間質軟骨肉瘤,並且討論其臨床表現、病理、影像檢查、治療與預後。 |
英文摘要 | Mesenchymal chondrosarcomas are rare malignant tumors of the bone and soft tissue. Extraskeletal mesenchymal chondrosarcomas, especially those that arise in the central nervous system, are even rarer. Most of those described were intracranially located, with only a very few cases having been reported in an intraspinal region. Therapeutic experience with primary spinal mesenchymal chondrosarcomas is also extremely limited. We report on a case of a 21-year-old man with back pain and bilateral progressive weakness and numbness of the lower extremities. A T1-weighted magnetic resonance image revealed a hypointense tumor located at the T8 level. The tumor was completely excised through a posterior approach. Microscopic examination and immunohistochemical studies confirmed the diagnosis of mesenchymal chondrosarcoma. Spinal irradiation and chemotherapy were also administered for prevention of local recurrence and metastasis. The patient has been symptom-free for 1 year after surgery. Herein, we review the 22 cases of primary intraspinal mesenchymal chondrosarcomas in the literature and discuss their clinical presentations, pathology, imaging studies, treatments, and outcomes. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。