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題名 | Acrodermatitis Continua of Hallopeau--A Case with Lesions Localized at Bilateral Thumbs Successfully Treated with Dapsone=Hallopeau連續性肢端皮膚炎--一病灶侷限於兩側姆指並成功以Dapsone治療之病例 |
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作者 | 楊弘旭; 陳信吉; 陳秀琴; 吳育弘; 蘇信義; | 書刊名 | 中華皮膚科醫學雜誌 |
卷期 | 21:2 2003.06[民92.06] |
頁次 | 頁165-170 |
分類號 | 415.684 |
關鍵詞 | 連續性肢端皮膚炎; Acrodermatitis continua of hallopeau; ACH; Dapsone; Psoriasis; |
語文 | 英文(English) |
中文摘要 | 一位六十六歲男性,兩年多來於雙手拇指罹患有連續性肢端皮膚炎具痛感之膿疱疹,並伴隨有指甲失養以及明顯的手部功能喪失。施以局部類固醇軟膏,煤焦油和calcipotriol軟膏皆無法改善其肢端病灶,因而開始以dapsone每日200mg治療。肢端病灶在療程第二週就有顯著改善。於是嘗試將dapsone減至每日150mg,但卻隨即有新的膿疱出現。將dapsone 劑量增加回每日200mg後,肢端病灶再度獲得明顯改善。在六週的治療期間內並無與dap- sone相關的副作用產生。停藥後個月追蹤並無復發跡象,而新指甲也開始長出。 |
英文摘要 | A 66-year-old male suffered from painful pustular eruptions of acrodermatitis continua of Hallopeau on bilateral thumbs for about 2 years, with associated nail dystrophy and markedly disabled manual skills. Initial treatment with topical corticosteroids, tars and calcipotriol failed to improve the acral lesions. Dapsone therapy began at a dose of 200 mg/day, which cleared the acral lesions within two weeks of therapy. However, new lesions relapsed when the dose was tapered to 150 mg/day. Increasing dapsone back to 200 mg/day was followed by another clearance of the acral pustules. During a total course of 6-week therapy, no dapsone-related side effects were noted. The patient remained symptom-free and nail growth was noted at the follow-up visit 3 months after the medica- tions were discontinued. |
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