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題 名 | 鈣應性--病例報告=Calciphylaxis--A Case Report |
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作 者 | 張啟杉; 劉明真; 劉漢南; | 書刊名 | 中華皮膚科醫學雜誌 |
卷 期 | 21:1 2003.03[民92.03] |
頁 次 | 頁75-81 |
分類號 | 419.67 |
關鍵詞 | 鈣應性; 末期腎疾病; Calciphylaxis; End-stage renal disease; |
語 文 | 中文(Chinese) |
中文摘要 | 鈣應性(calciphylaxis)是發生於末期腎疾病(end-stage renal disease)的一個少見及致死的併發症。臨床上所見為肢體疼痛紅斑性斑塊,隨著病程進行而發展成壞死性潰瘍。在顯微鏡下,真皮層與皮下組織之小型及中型動粵之肌肉層(fmedium) 鈣化為其特徵。一位65歲慢性腎衰竭女性病患,兩側下肢出現疼痛及壓痛之皮膚硬化,且左右小腿病灶上各有一潰瘍,於潰瘍邊緣施行皮膚切片後,其皮膚組呈現表皮壞死、皮膚血管栓塞、血管壁鈣化、以及鈣化性脂層炎(calciphying panniculitis)。綜合病人的臨床病史、皮膚的臨床懷徵和組織病理變化,診斷為鈣應性。 |
英文摘要 | Calciphylaxis is a rare and life-threatening condition, which occurs as a severe complication in patients with end-stage renal disease. Clinically, it manifests as painful erythematous and violaceous nodules, plaques and then progresses to necrotic ulcers on extremities. Under microscope, calcification in the medium of small and medium-sized vessels in the dermis and subcutis is the hallmark diagno- sis. A 65 year-old female with end-stage renal disease presented with painful and tender indurated ulcers on both lower legs. A skin biopsy undertaken nearby the ulcers demonstrated epidermis necro- sis, dermal vessel thrombosis, mural vessel calcification and calciphying panniculitis. By the virtue of clinical history, cutaneous manifestations and histopathologic findings, calciphylaxis was diagnosed. |
本系統中英文摘要資訊取自各篇刊載內容。