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題 名 | Magnetoencephalographic Characteristics of Interictal Spikes in TLE=內側顳葉癲癇患者之癲癇棘波在腦磁圖所見之特徵 |
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作 者 | 林永煬; 姚俊興; 尤香玉; 謝仁俊; 關尚勇; 顏得禎; 張開屏; 施養性; 黃棣棟; | 書刊名 | Acta Neurologica Taiwanica |
卷 期 | 12:1 2003.03[民92.03] |
頁 次 | 頁15-23 |
分類號 | 415.932 |
關鍵詞 | 內側顳葉; 癲癇棘波; 腦磁圖; Magnetoencephalography; Source localization; Interictal spikes; Mesial temporal lobe epilepsy; Temporal lobectomy; |
語 文 | 英文(English) |
英文摘要 | Purpose: To characterize the localization of interictal spikes by magnetoencephalography (MEG) in patients with mesial temporal lobe epilepsy (TLE). Methods: We studied 5 patients with mesial TLE who had convergent localization information based on presurgical evaluation and became seizure free after anterior temporal lobectomy (ATL). Simultaneous MEG and scalp EEG were recorded before and 6-12 months after surgery using a whole-scalp neuromagnetometer. We visually searched interictal spikes simultaneously occurring on both MEG and EEG channels and analyzed the spikes by MEG dipole modeling. Results: Spikes were localized in anterior temporal region, although most spikes were not exactly located in mesial temporal structure. The dipole orientation was horizontal for 86% (83-94%) of interictal spikes in 4 patients and vertical for 86% of interictal spikes in 1 patient. According to the postoperative MR images with superimposed spike coordinates, 91% (68-100%) of preoperative spike dipoles were situated within the resection demarcation of ATL. Conclusions: In patients with mesial TLE, most interictal spikes were localized in anterior temporal lobe within the resection demarcation of ATL. The dipole orientation can be either horizontal or vertical. |
本系統中英文摘要資訊取自各篇刊載內容。