查詢結果分析
來源資料
相關文獻
- Clinical Assessment of Amelanotic Malignant Melanoma: A Retrospective Study in Eastern Taiwan
- 腦中風患者吞嚥功能臨床評估可靠性之探討
- Molecular Analysis and Prenatal Diagnosis of β-Thalassemia in Taiwanese: A Current Status Review
- 專家系統振動訊號圖型判別之研究
- 以QBC[feb9]血液寄生蟲檢測法診斷瘧疾之效率
- Prenatal Diagnosis and Postnatal Management of Fetal Neuroblastoma: Report of Four Cases
- Preoperative Ultrasonographic Diagnosis of Occult Epigastric Hernia Presenting with Recurrent Abdominal Pain: Report of a Case
- Prenatal Diagnosis and Perinatal Outcome of Facial Clefts
- Prenatal Diagnosis of Lethal Osteogenesis Imperfecta: Report of a Case
- 荔枝園營養調查與營養診斷研究
頁籤選單縮合
題名 | Clinical Assessment of Amelanotic Malignant Melanoma: A Retrospective Study in Eastern Taiwan=無黑色素惡性黑色素瘤之臨床分析--東臺灣地區回溯性研究 |
---|---|
作者 | 孫宗伯; 許永祥; 簡守信; 郭文勵; 鄭立福; 李俊達; | 書刊名 | 慈濟醫學 |
卷期 | 15:1 2003.02[民92.02] |
頁次 | 頁13-19 |
分類號 | 415.691 |
關鍵詞 | 惡性黑色素瘤; 無黑色素; 診斷; 肢端黑痣型; 東臺灣; Malignant melanoma; Amelanotic; Diagnosis; Acral lentigenous; Eastern Taiwan; |
語文 | 英文(English) |
中文摘要 | 目的:肉眼可察覺之色素沉著,為臨床上診斷惡性黑色素瘤重要的線索之一。無黑色素惡性黑色素瘤,因極少或無色之表現,往往相當難以與其他多種良性或惡性的病灶區分。本研究之目的在於,歸納及記錄過去十二年來治療無黑色素惡性黑色素瘤之臨床表徵及病程,以作為對未來之病患處置之參考。病人與方法:回顧1989年九月至2002年三月間,於佛教慈濟綜合醫院確定診斷為惡性黑色素瘤之病患,對於其中無黑色素惡性黑色素瘤患者之表症狀、初期診斷、治療方法、病程發展及預後,加以記錄分析。結果:共有41位病人被診斷為惡性黑色素瘤,其中5位為無黑色素惡性黑色素瘤,發生率佔惡性黑色素瘤的12.2%,較相關報告之2%至8%為高。其表現症狀為3例指(趾)甲床下病灶、1例足底潰瘍、1肘部下結節。初期診斷包括肉瘤及鱗狀上皮細胞瘤。結論:無黑色素惡性黑色素瘤佔所有惡性黑色素瘤之比例,並非如傳統知之罕見,由於臨床診斷不易且難以與多種病灶區分,保持高度的懷疑、適時採取切片檢查、以及配合組織免疫染色,為建立無黑色素惡性黑色素瘤診斷之要件。 |
英文摘要 | Objective: Clinically perceptible pigmentation is the cardinal feature for suggestion of malignant melanoma. Amelanotic malignant melanoma may mimic a variety of benign and malignant lesions. The purpose of this study was to introduced our experience in managing amelanotic melanoma during the pat 12 years. Patients and Methods: after retrospectively reviewing the charts, all patients with established diagnoses of malignant melanoma form September 1989 through March 2002 were enrolled in this study. Subtype of amelantoc malignant melanoma was further stressed. The diagnosis of amelanotic malignant melanoma was confirmed using the characteristic pathologic findings of melanoma and the results of associated immunihostiochemical stains. The presenting symptoms, initial diagnoses, treatments, clinical courses, and outcomes were recorded. Results: There were 41 patients with malignant melanoma diagnosed in Buddhist Tzu chi General Hospital during the past 12 years. Diagnosis of amelanotic melanoma was made for five cases. The incidence of amelanotic presentations in patients with malignant melanoma in our series was 12.2%, which was higher than was higher than the reported incidence of 2% to 8% in some Caucasian series. The presenting symptoms were three subungual lesions, one plantar ulcer, and one subcustaneous nodular lesion of the elbow. Initial diagnoses included sarcoma and squamous cell carcinoma. Conclusion: According to the results of our study, amelantoic malignant melanoma is not an uncommon subtype of melanoma in eastern Taiwan. Since it may mimic may different lesion, highly clinical suspicion, biopsy of suspected lesions and proper use of immunohistochemical stain are the keys for establishing the diagnosis. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。