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題名 | 續發於植皮捐贈處之麥卡細胞瘤?--病例報告=Secondary Merkel Cell Carcinoma in Skin Donor Site?--A Case Report |
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作者姓名(中文) | 張家綺; 鄭詩宗; 陳國熏; 余幸司; | 書刊名 | 中華皮膚科醫學雜誌 |
卷期 | 20:4 2002.12[民91.12] |
頁次 | 頁318-323 |
分類號 | 415.78 |
關鍵詞 | 麥卡細胞瘤; 皮膚腫瘤; Merkel cell carcinoma; Donor site; Metastatic; |
語文 | 中文(Chinese) |
中文摘要 | 麥卡細胞瘤為一不常見之皮膚腫瘤,主要單發於老年人之頭頸部,且易轉移至肝,肺,骨頭,腦等遠處器官。然而,腫瘤細胞續發於植皮捐贈處為以往文獻所未記載。吾人報告一例於對側大腿之植皮捐贈處發現一“繼發性”麥卡細胞瘤。繼發性MCC機轉仍不明,可能原因有:因手術操作導致術中腫瘤細胞植入、經由淋巴轉移、經由血流蝀移、節二個原發性腫瘤等等。本文將有詳細討論。 |
英文摘要 | Merkel cell carcinoma (MCC) is an uncommon cutaneous neoplasm that mainly occurs solitarily in the head and neck region of the elderly. Systemic metastasis to distant organs, such as liver, lung, bone, and brain, is common. However, secondary occurrence of the tumor cells to skin donor site has not been reported previously. We reported one case that a “secondary” MCC appeared in the split-skin donor site on the contralateral thigh. The mechanism of this “secondary” MCC still remains unknown. We propose the probable causes are: intra-operative implantation, metastases in the lymphatics, metastases in the blood stream, and second primary tumor. |
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