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頁籤選單縮合
題 名 | Primary Carcinoid Tumor of the Testis: Case Report=原發性睪丸類癌瘤 |
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作 者 | 張英勛; 莊正鏗; 吳俊德; 吳桂芳; 廖順奎; | 書刊名 | 長庚醫學 |
卷 期 | 25:10 2002.10[民91.10] |
頁 次 | 頁695-699 |
分類號 | 415.87 |
關鍵詞 | 睪丸類癌瘤; 睪丸腫瘤; 超音波; Carcinoid tumor; Testis tumor; Ultrasound; |
語 文 | 英文(English) |
中文摘要 | 睪丸類癌瘤是相當少見的疾病。大部分類癌瘤發生在闌尾或迴盲腸,其餘可發生肺、肝臟和泌尿生殖系統。原發性睪丸類癌瘤可源自gentaffinar或Kulchitsky細胞。手術前超音波可見到實心、低回音且邊緣清楚的腫瘤,鑑別診斷包括畸胎瘤、胚胎細胞瘤、表皮樣瘤、結核病型副睪睪丸炎合併外傷。根治性睪丸切除仍然為睪丸類癌瘤的主要治麗方法。大體上睪丸類癌瘤為一茶褐色到白色實心腫瘤。在免疫組織化學染色上,睪丸類癌瘤對於Keratin AE1和AE3,chromogranin-A,neuron-specific enolase 和synaptophysin呈陽或反應。在治療上,原發性睪存類癌瘤一般被當成良性病灶處理,若是轉移性睪丸類癌瘤則預後相當不好。為了排除睪丸類癌瘤不是從其他地方轉移而來,因此手術後全身檢查是相當當重的。胸部X光,胸部、腹部和骨盆腔電腦斷層掃描,octreotide閃爍攝影都圖加以幫忙。我們提出一睪丸類癌瘤之病例報告,討論其超音波之表現,並回顧文獻之報導。 |
英文摘要 | Carcinoid tumor of the tests is exceedingly rare. Most carcinoid tumors occur in the appendix or ileocecal region (85%), while others are found in the lung, liver, and genitourinary tract (15%). A primary acrcinoid testis tumor may originate from argentaffin or Kulchistky’s cells, which ar located in the Lieberkuhn crypt. Preoperative ulatasound may show a soild, hypeochoic, well-defined margin mass combined with calcification or a cyst. Differential diagnosis of the ultrasound appearance is testicular tumor (teratoma/embryonal cell carcinoma), epidermoid tumor, tuberculous epididymo-orchitis, and the result of trauma. Radical orchiectomy remains the main treatment for a carcinoid testis tumor. Grossly, surgical removal of the tumor presents with a solid mass, tan to white in color. Immunohistochemical study shows that tumor cells are diffusely reactive to antibodies to keratins AE1 and AE3, chromogranin-A, neuron-specific enolase (NSE), and synaptophysin. A pure primary testicular carcinoid tumor has been treated as a beign lesion, while metastatic carcinoid tumor has a poor prognosis regardless of the primary site. To rule out the possibility of metastasis resulting from an extra-testicular primary carcinoid, careful and thorough postoperative whole body surveys are important. Chest X-ray, chest computed tomogram(CT), abdominal and pelvic CT, and octreotide scintigraphy are indicated. We herein describe a case of primary carcinoid tumor of the testis and review the literature. |
本系統中英文摘要資訊取自各篇刊載內容。