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頁籤選單縮合
題名 | Serum γ-Glutamyl Transpeptidase Activity and Bile Acids in Normal Taiwanese Infants=正常臺灣嬰兒之血清γ-GT活性及膽酸值測試 |
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作者 | 黃裕智; 陳慧玲; 蔡克嵩; 唐禎瑞; 倪衍玄; 張美惠; | 書刊名 | 臺灣兒科醫學會雜誌 |
卷期 | 43:5 民91.09-10 |
頁次 | 頁245-248+298 |
分類號 | 414.81 |
關鍵詞 | γ-GT活性; 膽酸; 參考值; γ-glutamyl transpeptidase activity; γ-GT; Bile acids; Reference ranges; |
語文 | 英文(English) |
中文摘要 | 爲了有利於在臺灣對於膽汁滯留性肝臓疾病之診斷,我們建立正常臺灣嬰兒之血清γ-GT活性及膽酸參考值。γ-GT活性是分析90位年齡分佈由兩個月到兩歲的正常臺灣嬰幼兒之血清,其中23位爲0至3個月,24位4至6個月,43位7至24個月。結果γ-GT活性之平均值分別是在0至3個月嬰兒爲47.4±26.6IU/L, 在4至6個月嬰兒爲21.5±7.3IU/L,在7至24個月嬰幼兒爲14.0±3.2IU/L。此結果顯示γ-GT活性在3個月以下之嬰兒最高,之後隨年紀增加逐漸降至成人值。血清膽酸值之分析則來自24位早産及56位足月新生兒,其平均值在早産兒爲34.5±34.5μmol/L,在足月兒爲18.7±21.9μmol/L,血清膽酸值在早產兒顯著高過足月兒(p<0.01). |
英文摘要 | To facilitate making a diagnosis of cholestatic liver disease in Taiwan, we have established reference ranges for serum γ-glutamyl transpeptidase (γ-GT) activity and bile acids in normal Taiwanese infants. The serum level of γ-GT activity was assayed in 90 normal Taiwanese infants and children aged between 2 days and 2 years old. These data were analyzed in twenty-three 0~3-month-old, twenty-four 4~6-month- old, and forty-three 7~24-month-old infants. The mean values of serum γ-GT activity were 47.4 ±26.6, 21.5±7.3, and 14.0 ±3.2IU/L for the respective age groups. The highest reference γ-GT values were 99.5, 35.8, and 20.3IU/L for the respective age groups. The mean values of serum γ-GT activity were highest in infants younger than 3 months, and these gradually decreased to the adult level with age (p<0.01). Serum bile acids were measured in 24 premature and 56 full-term infants. The mean values of serum bile acids were 34.5±34.5μmol/L in preterm infants and 18.7±21.9μmol/L in full-term babies. The bile acid levels of preterm infants were higher than those in full-term babies (p<0.01). |
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