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頁籤選單縮合
題名 | Esophageal and Gastric Kaposi's Sarcomas Presenting as Upper Gastrointestinal Bleeding=以上消化道出血來表現的食道及胃之卡波希氏肉瘤 |
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作者 | 林政輝; 許朝偉; 江仰仁; 吳桂芳; 邱正堂; | 書刊名 | 長庚醫學 |
卷期 | 25:5 2002.05[民91.05] |
頁次 | 頁329-333 |
分類號 | 415.51 |
關鍵詞 | 卡波希氏肉瘤; 上消化道出血; 腎臟移植; Kaposi's sarcoma; Upper gastrointestinal bleeding; Renal transplantation; |
語文 | 英文(English) |
中文摘要 | 卡波希氏肉瘤是一種少見的間質組織惡性腫瘤,常發生於免疫功能不全的患者以及地中海沿岸的居民。通常好發於男性,以皮膚的病變為主。然而在接受器官移植的患者身上,也常有內臟器官的病變,消化道是內臟器官病變的好發部位之一。發生在消化道的卡波希氏肉瘤通常是沒有症狀的。我們報告一位41歲女性病人,接受腎臟移植後,正在服用免疫抑制劑,人類免疫缺乏病毒檢驗為陰性,因為雙側頸部及會陰部淋巴腺腫大和解黑便住院。胃鏡檢查發現在食道及胃有一些紅紫灰色的斑塊,並且在胃�埵酗@班塊正在出血。組織學檢查顯示紡錘形細胞增生及血管性裂口出血,診斷為卡波希氏肉瘤。卡波希氏肉瘤引起的胃出血則以局部注射合併熱探子治療,之後追蹤並未有出血。這些病變在改變免疫抑制劑的處方後消失。 |
英文摘要 | Kaposi’s sarcoma (KS) is an uncommon malignant neoplasm of mesenchymal tissue that occurs in immunocompromised patients and people of Mediterranean descent. It is most common in males, and skin lesions are usual presentations. However, visceral lesions are common in organ transplant recipients and involve the gastrointestinal tract. Although the gastrointestinal tract is a site for extracutaneous lesions, most lesions are asymptomatic. Herein, a case of a 41-year-old female with cadaveric renal transplantation and immunosuppressive therapy but without human immunodeficiency virus infection is reported. She was admitted due to tarry stool passage and bilateral neck and inguinal lymph node enlargement. Esophagogastroduodenoscopy revealed multiple grayish-purple plaques in the esophagus and stomach with active oozing from one of the stomach lesions. Histological examination demonstrated characteristic spindle cell stroma and vascular slits with hemorrhage. Furthermore, KS was the impression. The site of gastric bleeding produced by KS was injected locally with bosmin 1:10,000, and heat probe coagulation was performed. No further bleeding was discovered during follow-up. Following modification of the immunosuppressive therapy regimen, the lesions disappeared. |
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