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題名 | Bilateral Orbital Kimura's Disease in a Young Asian Man=一位亞裔青年之眼窩木村氏症 |
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作 者 | 楊曄; 馬俐; | 書刊名 | 長庚醫學 |
卷期 | 25:1 2002.01[民91.01] |
頁次 | 頁45-50 |
分類號 | 416.75 |
關鍵詞 | 眼窩木村氏症; 血管淋巴性增生併嗜伊紅性血球昇高; Orbital kimura's disease; Angiolymphoid hyperplasia with eosinophilia; |
語文 | 英文(English) |
中文摘要 | 一位16歲之亞裔青年在最近一年內患有雙側眼瞼腫脹合併多顆皮下腫塊,此症狀會因類固醇之治療而減緩,但停藥後往往又隨即加重。病人除了在過去9年內患有雙側耳後淋巴腺腫脹,身體大致健康。實驗室檢查顯示了周遭嗜伊紅性血球增加及E型免疫球蛋白升高之情形。左側眼窩腫塊經手術切除及眼皮整形後得到良好外觀效果。術後之電腦斷層未發現左側有任何殘餘腫塊,但在右側淚腺周圍,上直肌及外直肌之間深入眼窩處則可見這些軟組織腫塊。十天後另行手術把右側腫塊切除。病理切片顯示了許多淋巴濾泡組織併有活躍的生發中心,相當多的淋巴球及嗜伊紅性血球浸潤,為典型木村氏症之表現。術後經過7個月之追[]未發現有復發跡象。眼窩木村氏症為一罕見且好發於中、老年亞裔男性之疾病,但也可以偶見於青年人。經由手術完全切除及同時施行眼皮整形可以得到令人滿意之外觀效果。 |
英文摘要 | A 16-year- old Asian man adolescent presented with bilateral eyelid swelling with multiple palpable mass lesions, which waned after treatment with corticosteroids but waxed after medications were discountinued, for about 1 year. He was otherwise healthy except that bilateral postauricular lymphadenopathy had developed for about 9 years. Laboratory study revealed peripheral ensinophilia with an elevated IgE level. The tumor masses of the left orbit were completely excised through an incision similar to that used in blepharoplasty, which gave good cosmetic results. Postoperative computed tomography scan showed no residual tumor mass in the left orbit but contralateral homogeneous soft-tissue mass lesions around the lacrimal gland and extending deep into the orbit, between the superior and lateral rectus muscles. Pathology reported numerous lymphoid follicles with active germinal centers and extensive lymphocyte and eosinophil infiltration, which characterize Kimura's disease (KD). The tumor mass in the right orbit was also excised during a second elective surgery 10 days later. No evidence of recurrence was noted after follow-up for 7 months. KD of the orbit is rare and usually occurs in middle-aged to elderly Asian men but can also KD of the orbit is rare and usually occurs in middle-aged to elderly Asian men but can also be present in young adolescent. Complete excision with simultaneous blepharoplasty gives satisfactory cosmetic results. |
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