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題 名 | Livedoid Vasculopathy--Report of One Case Treated with Warfarin=青斑樣血管病變--以Warfarin治療之病例報告 |
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作 者 | 黃逸明; 胡俊弘; 李婉若; | 書刊名 | 中華皮膚科醫學雜誌 |
卷 期 | 20:1 2002.03[民91.03] |
頁 次 | 頁51-56 |
分類號 | 415.74 |
關鍵詞 | 青斑樣血管病變; Livedoid vasculopathy; Warfarin; |
語 文 | 英文(English) |
中文摘要 | 青斑樣血管病變是一種慢性疾病,臨床上以足部、踝部與腿部反覆出現疼痛性潰瘍而癒合後留下萎縮性疤痕為特徵,組織學上則以血管內有纖維素沉澱為特徵。我們報告一個42歲男性,一年半來因在兩側下肢患有反覆發作的多發性之深部結痂潰瘍。對於傳統的治療包括dipyridamole、pentoxyphylline、與aspirin的反應皆非常差。Warfarin是一種口服的抗凝血劑,我們投以每日3.75mg至今約有兩個月。經Warfarin治療後即無新皮膚病變發生,原先之皮膚病變也得到明顯的改善。 |
英文摘要 | Livedoid vasculopathy is a chronic disorder characterized clinically by recurrent painful ulcers of the feet, ankles and legs that heal with residual white atrophic scars and histologically by intravascular deposition of fibrin. We report a 42-year-old man who has had recurrent multiple painful, deep-crusted ulcerations with erythematous bases over bilateral lower legs for one and a half years. Therapeutic response to dipyridamole, pentoxyphylline and aspirin was very poor. Oral anticoagulant, warfarin was administered at 3.75mg/day and maintained for 2 months. New lesions have not recurred and existing lesions have improved after 2 months. |
本系統中英文摘要資訊取自各篇刊載內容。