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題名 | Quercetin Glucuronides Inhibit the Growth of Human Acute Myeloid HL-60 Leukemia Cells |
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作者 | 郭秀滿; 李珮端; 鍾景光; | 書刊名 | 中華藥學雜誌 |
卷期 | 54:1 民91.02 |
頁次 | 頁17-24 |
分類號 | 414.33 |
關鍵詞 | 檞皮酮; Quercetin; Quercetin glucuronides; N-Acetyltransferase; 2-Aminofluorene; N-Acetyl-2-aminofluorene; HL-60; |
語文 | 英文(English) |
英文摘要 | We previously demonstrated that quercetin glucuronides could affect N-acetylation of 2-aminofluorene in human acute myeloid leukemia HL-60 cells. The present study examined the cytotoxicity of quercetin glucuronides to human acute myeloid leukemia HL-60 cells. Cell death was monitored by assessing morphological changes, nuclei condensation, viable cells, cell cycle phase arrest and DNA damage. Our result indicate that quercetin glucuronides can induce cell death of HL-60 cells. |
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