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題名 | 普利子疾病--庫賈氏病:一病例報告及文獻回顧=Prion Disease--Creutzfeldt-Jakob Disease: A Case Report and Review |
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作者 | 黃學謙; 鍾作謙; | 書刊名 | 內科學誌 |
卷期 | 13:1 2002.02[民91.02] |
頁次 | 頁43-48 |
分類號 | 415.84 |
關鍵詞 | 失智症; 肌躍症; 普利子疾病; 庫賈氏病; 搔羊形普利子蛋白; Dementia; Myoclonus; Prion disease; Creutzfeldt-Jakob Disease; CJD; Scrapie prion protein; PrP; |
語文 | 中文(Chinese) |
中文摘要 | 我國目前人口有兩千三百萬人,其中有超過一百六十萬人為六十五歲以上老人,意味著我國已邁入高齡化國家。老年人的生理機能及心智功能漸漸退化是老化的特性。如果一個老人在短期間內發生急速失智,並伴有一些難以解釋的神經學臨床表現,如步態蹣跚、不自主運動、肌躍症等,在排除了腦血管病變、感染以及代謝異常的可能性後,有必要去思考是否得了普利子疾病 (prion disease) 。雖然此病的發生機率只有百萬分之一,相當罕見,但是為了達到早期診斷,早期處理的目的,身為內科醫師有必要對此疾病做進一步的了解。 |
英文摘要 | Taiwan has a general population of 23 million with more than 1.6 million aging over 65 years-old. Mental and physiological retardation was noted over the aging process. If someone has unexplainable, acute onset of dementia associate with unpredictable neurological deficit such as ataxia, myoclonus, or akinesia, CreutzfeldtJakob Disease should be taken count into after excluding primary or secondary dementia such as vascular dementia, CNS infection, neoplasm, trauma and systemic metabolic problem. Hereby we present a 73 year-old female with the above clinical presentation. In order to have early diagnosis and early management towards CreutzfeldtJakob disease , it is necessary to know more about the CreutzfeldtJakob Disease. (J Intern Med Taiwan 2002;13: 43-48 ) |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。