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| 題 名 | 起源自腮腺深葉良性多形性腺瘤之腺癌:病例報告=Carcinoma ex Pleomorphic Adenoma of Deep Lobe of Parotid Gland--A Case Report |
|---|---|
| 作 者 | 楊政杰; 高壽延; 張哲壽; | 書刊名 | 中華民國口腔顎面外科學會雜誌 |
| 卷 期 | 12:1 2001.03[民90.03] |
| 頁 次 | 頁45-54 |
| 分類號 | 416.8 |
| 關鍵詞 | 腮腺; 多形性腺瘤; 惡性轉變; Carcinoma ex pleomorphic adenoma; Malignant transformation; |
| 語 文 | 中文(Chinese) |
| 中文摘要 | 腮腺之多形性腺瘤乃是唾液腺最常見的腫瘤,約佔所有唾液腺良性腫瘤的百分之六十至七十,這類的腫瘤在臨床土的表現常是耳下緩慢增生的年無痛性腫塊,臨床上診斷的依據必須配合臨床檢查、電腦斷層掃描、磁振造影及細針抽取切片的病理檢查方可得知,其治療方式主要是對腫瘤進行局部切除手術 (local excision) 或腮腺的切除手術 (parotidectomy),手術中顏面神經需小心保留,但須將腫瘤的外膜部分切除乾淨,診斷及治療計畫著重在預防腫瘤復發及腫瘤產生惡性轉變。而由良性多形性腺瘤,產生惡性轉變而來的惡性混合瘤 (malignant mixed tumor),通常起源於長期存在的良性腫瘤,這類的惡性腫瘤五年的復發率為75%,比率非常高,因此除手術大範圍切除外,常需配合手術後的放射線治療。本文提出一原診斷為腮腺良性多形性腺瘤之病例,徑四年長期追蹤後,進行手術切除,病理診斷證實已轉變為惡性之多形性腺瘤。 |
| 英文摘要 | Pleomorphic adenoma is the most common gland tumor of parotid origin, accounting for 60 to 70%. This kind of tumor usually presents as a slow-growing painless mass antero-inferior to the ear. The diagnosis is based on physical examination, image studying and even fine needle aspiration biopsy. The optimal method of treatment of such tumors is local excision or paroidectomy in which the entire capsule is totally dissected off but the facial nerve is spared. Diagnosis and treatment planning are focused on preventing tumor recurrence and consequent malignant transformation. Carcinoma ex pleomorphic adenoma which mean “carcinoma arising from previous existed pleomorphic adenoma” has a high 5-year recurrent rate of 75%. So its treatment should be a combined modality of surgical excision and radiotherapy. Here we presented a case of benign pleomorphic adenoma of the deep lobe of left parotid gland proved by fine needle aspiration biopsy 4 years ago. Finally the tumor came up to be a pleomorphic adenoma after the tumor had been removed. |
本系統中英文摘要資訊取自各篇刊載內容。