查詢結果分析
來源資料
相關文獻
- Measurement of Serum Vitamin E Isomers in Fullterm and Preterm Infants
- 早產兒視網膜病變眼科與新生兒科醫師之聯合照顧
- 新生兒/早產兒水份、電解質治療
- Noise Distribution of an Incubator with Nebulizer at a Neonatal Intensive Care Unit in Southern Taiwan
- Noise and Related Events in a Neonatal Intensive Care Unit
- Auditory Brainstem Evoked Potentials in Healthy Full-Term and Pre-Term Infants
- 新生兒加護病房藥物血中濃度療效監測案例--Aminophylline治療早產兒短暫窒息
- Breast Milk and the Prevention of Neonatal and Preterm Gastrointestinal Disease States: A New Perspective
- 新生兒感染之病例用藥評估
- Surgical Closure of Patent Ductus Arteriosus in Preterm Infants at Neonatal Intensive Care Unit
頁籤選單縮合
題名 | Measurement of Serum Vitamin E Isomers in Fullterm and Preterm Infants=足月兒及早產兒血中維生素E含量之測定 |
---|---|
作 者 | 吳淑娟; 周怡宏; | 書刊名 | 長庚醫學 |
卷期 | 24:12 2001.12[民90.12] |
頁次 | 頁793-798 |
分類號 | 417.517 |
關鍵詞 | 維生素E; 新生兒; 早產兒; 高相液體層析法; Vitamin E; Neonates; Preterm; High-performance liquid chromatography; |
語文 | 英文(English) |
中文摘要 | 背景:維生素E是一種脂溶性的抗氧化物,與生?的某些疾病(例如慢性肺部病變)有相當的關係,然而由母體通過胎盤傳遞給胎兒的維生素E很少。有的目的在測定新生兒血液中維生素E的含量,並試圖找出較適合測定體內維生素E的方法。 方法:本研究蒐羅1996年9月至1997年2月,共34對足月兒(妊娠週數:38-42週,?生體重:2340-3530克)剛出生之靜脈血。再以高相液體層析法定量這些血液中維生素E(α及γ形態異構物)的含量。同時也比較維生素E及血脂肪之比值。 結果:(1)足月兒及其母親之α-維生素E-和γ-維生素E分別為,α:0.212±0.127 mg/dl,1.160±0.513 mg/dl,γ:0.029±0.019 mg/dl,0.214±0.122 mg/dl,母親都較嬰兒高出許多;(2)就血液中維生素e及脂肪的比值,足月兒及其母親之間也有顯著的差異;(3)在早產兒中,其維生素E分別為α:0.170±0.090 mg/dl,γ:0.020±0.015 mg/dl;都低於足月兒,但是就血液中維生素E及脂肪的比值,兩組則相差不多,(4)不論是足月兒或是早產兒,其維生素E都顯著不足(0.5 mg/dl)。 結論:以高相液體層析法來測定維生素E的含量,即使在易有維生素E缺乏的族群中也是可行的。吾人發現新生兒血中的維生素E普遍都不足,尤其是早產兒族群。 |
英文摘要 | Background: This study was conducted with the following aims: (1) to construct a methodology by high-performance liquid chromatorgraphy (HPLC) to measure vitamin E levels in our neonatal units; (2) to establish a reference range of serum vitamin El levels in fullterm neonates and their mothers; and (3) to compare these to levels in the preterm group. Methods: During a 6-month period from September 1996 to February 1997, cord blood of 340 uneventful fullterm neonates (gestational age 38-42 weeks, birth weight 2840-3530 g) and venous blood of their healthy mothers were collected. Venous blood of 35 preterm neonates (gestational age 28-34 weeks, birth weight 940-1980 g) was collected at the same time. Serum vitamin E levels were measured by HPLC. The serum vitamin E/total lipids ratio was also examined. Results: Serum levels of α-tocopherol in 34 fullterm neonates and their mothers were 0.212±0.127 and 1.160±0.513 mg/dl, and of γ-tocopherol were 0.029±0.019 and 0.214±0.122 mg/dl, respectively. All fullterm neonates except 2 had serum levels less than 0.5 mg/dl. There was a positive relationship between serum E levels and total lipids. In addition, the correlation between neonatal vitamin E/ total lipids ratios and maternal vitamin E/total lipids ratio was statistically statistically significant. The serum level of α-tocopherol in 35 preterm infants was 0.170±0.090 mg/dl and that of γ-tocopherol was 0.20±0.015 mg/dl; both levels were much lower than those of their fullterm counterparts. But the vitamin E/total lipids ratios did not significantly differ. Conclusions: We conclude that (1) measurement of serum vitamin E levels by the HPLC method is practical, and is useful in evaluating deficiencies in preterm infants and possibly useful in monitoring the adequacy after supplementation in future study, and (2) preterm infants had a much lower level of serum tocopherol, but no difference was seen in vitamin E/total lipids ratio. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。