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題名 | Two Episodes of Ethylene Oxide Poisoning--A Case Report=兩次環氧乙烷中毒事件--病例報告 |
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作者姓名(中文) | 林增記; 何啟功; 陳成裕; 蔡錦蓮; 蔡米山; | 書刊名 | The Kaohsiung Journal of Medical Sciences |
卷期 | 17:7 2001.07[民90.07] |
頁次 | 頁372-376 |
分類號 | 418.82 |
關鍵詞 | 環氧乙烷中毒; Ethylene oxide; Toxicity; Occupation; Protective equipment; |
語文 | 英文(English) |
中文摘要 | 環氧乙烷可作為殺菌劑、溶劑及塑化劑,並可用來製造特殊溶劑、抗 凍劑、聚酯樹酯及非離子介面活性劑,其毒性是來自於身體許多有機物質被其烷 基化。民國八十九年七月二十九日四名員工,沒有帶任何防護設備,不當地處理 由儲毒系統大量外溢的環氧乙烷。民國八十九年八月七日,同一工廠在製造過程 中,因環氧乙烷不慎流量過大,不幸環氧乙烷排出過多,造成環氧乙烷再次外漏, 兩員工進行處理,帶有全面式含環氧乙烷濾毒罐防護面罩,但因濃度過高,濾毒 罐飽合失效,兩位員工因此而中毒。六位員工均有聞到乙醚樣之味道,以噁心、 嘔吐、胸悶、喘、頭暈、咳嗽、眼刺激為臨床表徵,有一人暫時性的意識不清, 經氧氣給予及支持性之療法,均痊癒回至工作崗位。環氧乙烷八小時空氣中平均 工作容許濃度是1 ppm,大於 50 ppm則會聞到味道,且需要正壓式供應呼吸裝 置之防護設備保護工作者,全面式含環氧乙烷濾毒罐防護面罩,無法保護這兩次 事件,有關到味道及不知毒物濃度之工作者,因此攜帶自攜、正壓式呼吸裝置合 併全面式防護面罩之防護設備去清除污染及解救病人是相當重要的。 |
英文摘要 | Ethylene oxide is used as a sterilizer, a solvent, a plasticizer and in the manufacture of special solvents, antifreeze, polyester resins and non-ionic surfactants. Its toxicity is caused by an alkylating reaction with most organic substances in the body. Four workers, without any protection, managed the leakage of ethylene oxide from the collecting tank improperly on July 29, 2000. In the same factory, the overflow of ethylene oxide in process resulted in leakage of ethylene oxide again on Aug. 7, 2000. Two workers were poisoned despite wearing full-face respirators with ethylene oxide approved canisters. In these two events, the workers all smelled an ether-like odor. Six workers experienced nausea, vomiting, chest tightness, shortness of breath, dizziness, cough and ocular irritation. One worker had transient loss of consciousness. Oxygen therapy and supportive care were used. Patients were discharged in stable condition. The permissible exposure limit of ethylene oxide in air is 1 ppm as an eight hour TWA. Above 50 ppm , the odor threshold, a positive-pressure supplied air respirator is needed to protect the worker. Full-face respirators with ethylene oxide approved canisters could not protect our cases who smelled the odor and were exposed to an unknown concentration. It is important to wear positive-pressure self-contained breathing apparatuses equipped with full facepieces to clean up the contamination area and rescue the patients. |
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