查詢結果分析
來源資料
頁籤選單縮合
題名 | 臺糖公司豬日本腦炎之研究: 疫學、免疫適期及疫苗免疫效益=Studies on Japanese Encephalitis of Swine in TSC: Epidemiology, Optimal Vaccination Program, and Efficacy of Vaccine |
---|---|
作者 | 廖朝政; 朱光寧; 俞寶華; 彭春乾; Liao, C. C.; Chu, K. N.; Yu, P. F.; Poun, T. C.; |
期刊 | 臺糖畜產 |
出版日期 | 19980300 |
卷期 | 3:4 1998.03[民87.03] |
頁次 | 頁41-58 |
分類號 | 437.245 |
語文 | chi |
關鍵詞 | 日本腦炎; 血球凝集反應; 血球凝集抑制反應; 疫學; 免疫; 豬; Jpanese encephalitis; HA; HI; Epidemiology; Vaccination; Swine; |
中文摘要 | 試驗1,異常產母豬及其胎兒之日本腦炎(Japanese encephalitis; JE) 血清學 與病毒學調查顯示,胎兒HI與HA陽性率分別為14.8%(4/27)與 22.2%(6/27),且電子顯 微鏡下觀察可發現JE病毒顆粒;應用BHK細胞株培養,亦可分離出JE病毒;由異常產母豬JE 之HI抗體變化顯示,部份母豬於感染後有明顯變化。試驗2,臺糖公司肉豬群JE抗體之消長 試驗顯示北區由6月至12月底止,中區由5月起至10月底止,南區由4月起至10月底止JE抗體 消失而轉陽性,顯示有感染情形;然經產母豬JE之HI抗體於冬季時(2月份)呈急遽下降, 尤其是第1,2及7產(平均力價分別是147.9、208.9及288.4倍)。試驗3,在JE疫苗免效益評 估上,比較經產母豬異常胎兒比率,以每胎均免疫的第1組之4.1%(15/365)異常產率最低 ,在流行期前免疫的第2組5.1%(18/354)次之,僅第1胎免疫的第3組9.0%(31/345)最高 ;且第 1、3組間差異極顯著(p<0.01),第2、3組間差異顯著(p<0.05)。女豬經2次免 疫之異常產率9.4%(16/170)顯著地(p<0.05)低於1次免疫的16.7%(27/162)。由上觀 之:母豬仍有JE感染引起異常產的疫情,越冬後母豬JE抗體會急遽下降應予補強。依據JE之 流行期判定,最佳補強時機為北區3∼7月,中區2∼6月,南區1∼5月。免疫效益評估結果, 經產豬以每胎均予免疫之效益最佳,女豬則於配種前完成2次免疫較佳。 |
英文摘要 | Of the 27 abnormal fetuses examined in Trial 1,4 fetuses (14.8%) were positive for HI test, and 6 fetuses (22.2%) were positive for HA test. In addition, virions of JE were isolated and detected under an electron microscope. In trial 2, the epidemic seasons of JE were from June to December in the northern, May to October in central, and April to October in southern Taiwan. The HI antibody titers against JEV of sows decreased rapidly in winter (February), especially in parities 1,2, and 7, whose geometric mean titers were 147.9, 208.9, and 288.4, respectively. The titers of pre-, postvaccination, and postpartum of group 1 were the highest (414.0, 548.6, and 586.4, respectively) among three groups. As to comparison of the ratio of abnormal fetuses, group 3 was the highest (9.0%, 31/345), group 1 was the lowest (4.1%, 15/365), and group 2 was intermediate (5.1%, 18/354). In the statistical analysis of abnormal fetuses, the values were highly significantly different between group 1 and group 2 (p<0.01) and significantly different between group 2 and group 3 (p<0.05). HI antibody titers of group 2 in experiment 2 were higher than for group 1 after vaccination (222.0 vs 80.5). The ratio of abnormal fetuses of group 2 (9.4%, 16/170) was significantly lower than for group 1 (16.7%, 27/162) (p<0.05). The study indicated that abnormal fetuses appeared in pregnant sows following subsequent natural JEV infection. The HI antibody titers against JEV of sows decreased rapidly in winter. The most suitable booster period against JEV in sows is suggested as being from March to July in the northern, February to June in the central, and January to May in the southern regions of Taiwan. A more effective and economically efficacious program for JE vaccination includes vaccinating twice by JE vaccine before mating in gilts and vaccinating once postpartum in sows. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。