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頁籤選單縮合
題名 | 免疫感測器之技術發展及其應用=Development of Techniques for Immunobiosensors and Their Applications |
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作 者 | 周淑芬; 陳建源; | 書刊名 | 化學 |
卷期 | 59:2 2001.06[民90.06] |
頁次 | 頁263-271 |
專輯 | 化學感測器專題 |
分類號 | 368 |
關鍵詞 | 免疫感測器; 物理轉換器; 螢光法; 冷光法; 壓電晶體微量天平; 表面聲波; 表面電漿共振; 波導; IAsys裝置; Immunosensor; Physical transducer; Fluorescence; Luminescence; Quartz crystal microbalance; Surface acoustic wave; Surface plasmon resonance; Waveguides; BIAcore; IAsys; |
語文 | 中文(Chinese) |
中文摘要 | 免疫感測器主要是由生物元件及物理轉換器二部分所組成。生物元件部分為抗體 與抗原之特異性反應;物理轉換器部分則包括直接或間接之訊號轉換系統。間接型之訊號轉 換系統係在抗體抗原反應後使用例如螢光法或冷光法等標示來進行檢測;直接型之訊號轉換 系統則係利用抗體抗原結合後所導致之電位、電流、電阻、質量、熱或光學性質之改變來檢 測,其優點為可即時 (real-time) 偵測抗原抗體反應情形。 免疫感測器具有高敏感度、高 特異性、所需樣品量少、低檢測低限、即時輸出、可重複使用等多項優點。目前已有少數之 免疫感測器如 BIAcore 及 IAsys 等裝置被成功商品化,可廣泛應用在臨床醫藥、環境保護 、發酵工業、以及科學研究等範疇。 |
英文摘要 | The main components of Immunosensor are composed of biological functional materials and physical transducers. The biological components perform the specific interaction between antigens and antibodies. The transducer components confer the direct and indirect trnasformation of signals. The indirect signal transforming system bases on the detection of the emission from coloring, fluoresc or luminesce materials labeled on antigens and/or antibodies. The direct signal tansforming system, on the other hand, bases on the detection of the deviation of potential, current, resistance, mass, heat, or optical characteristics during the immuno-reactio. The direct signal transforming system is advantageious on its ability of real-time monitoring of immuno-reactions. The merits of immunosensors include high sensitivity, high specificity, little sample rquirement, low detection limit, real-time output, and reusability. Powerful immunosensing systems, BIAcore and IAsys for example, have been well established and commercially available. They are widely applied in the fields of clinical analysis, environmental protection, fermentation industry, and scientific research. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。