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題 名 | Fatigue and Related Factors in Women with Breast Cancer Receiving Chemotherapy=化學治療乳癌病患之疲憊及其相關因素研究 |
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作 者 | 李惠玲; 鍾明惠; 趙詩瑾; 顧乃平; | 書刊名 | 醫學研究 |
卷 期 | 21:3 2001.06[民90.06] |
頁 次 | 頁123-133 |
分類號 | 416.226 |
關鍵詞 | 疲憊; 化學治療; 乳癌; Fatigue; Chemotherapy; Breast cancer; |
語 文 | 英文(English) |
中文摘要 | 本描述性研究目的在評值乳癌病患於化學治療前和化學治療後疲憊之改變,並了解與其相關之因素。研究對象為109位臺北地區三所教學醫院中接受化學治療之乳癌病患。研究工具包括Piper疲憊感受量表、Schwartz癌症疲憊量表、症狀困擾量表、情緒困擾量表、Eastern Cooperative Oncology Group身體功能狀況表。本研究之重要結果為:(1)乳癌病患在化學治療後的疲憊顯著增加(p<0.001);(2)疲憊與症狀困擾、情緒困擾、及身體功能狀況均呈顯著相關(p<0.001);慢性病史和化學治療藥物會影響乳癌病患的疲憊(p<0.05);逐步回歸分析顯示症狀困擾及情緒困擾兩個變項是Piper疲憊感受量表及Schwartz癌症疲憊量表的預測因子,分別可解釋51.8%和64.2%之變異量。結論為疲憊在乳癌病患化學治療後顯著增加,而症狀困擾、情緒困擾、及身體功能狀況為疲憊之相關因素。 |
英文摘要 | The purpose of this descriptive study is to investigate the changes in fatigue and its related factors of patients with breast cancer before and after chemotherapy. The subjects consist of 109 breast cancer patients receiving chemotherapy at the three medical centers in Taipei. The instruments included the Piper Fatigue Scale (PFS), the Schwartz Cancer Fatigue Scale (SCFS), the Symptom Distress Scale, the Mood Disturbance Questionnaire, and the Eastern Cooperative Oncology Group performance status. The main results are as follows: (1) Fatigue significantly increases after chemotherapy in comparison to the situation before chemotherapy (p<0.001); (2) Fatigue significantly relates to symptom distress, mood disturbance, and functional status (p<0.001). Previous medical disease history and chemotherapy regimens administered are also significantly related to fatigue (p<0.05). Further stepwise regression shows that both symptom distress and mood disturbance explain 51.8% by PFS and 64.2% by SCFS of the variance of fatigue. In conclusion, fatigue occurs significantly after chemotherapy for breast cancer patients and symptom distress, mood disturbance, and functional status are the related factors. |
本系統中英文摘要資訊取自各篇刊載內容。