頁籤選單縮合
題名 | 口腔疣狀癌:73個病例分析=Oral Verrucous Carcinoma: An Analysis of 73 Cases |
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作者 | 陳百立; 林正仲; 陳中和; | 書刊名 | 中華民國口腔顎面外科學會雜誌 |
卷期 | 11:1 2000.03[民89.03] |
頁次 | 頁11-17 |
分類號 | 416.94 |
關鍵詞 | 口腔疣狀癌; |
語文 | 中文(Chinese) |
中文摘要 | Ackerman於1948年首先提出口腔疣狀癌是一種生長緩慢的鱗狀細胞癌的異型,在臨床上不易與麟狀細胞癌或疣狀皮上增生來加以區別。其組織病理學土的特徵為正型或亞型上皮增生,上皮有向下推擠增生等變化,與疣狀上皮增生其他良性病變不易區分,必須仔細鑑剖診斷,而對於其致病因素與治療方法並未有一致結論。本研究針對高雄醫學大學自1992至1997年經診斷為口腔疣狀癌的73個為例作一臨床研究調查。西方世界的研究發現與煙草的使用有關,但在本研究發現在台灣地區嚼食檳榔是最重要的致病因子。好發部位依序為頰黏膜,唇與舌,且男性達多於女性,發病年齡有年輕化的趨勢。而不論是使用手術或放射線治療復發率都是相當高的,術後必須在臨床上做密切追蹤。 |
英文摘要 | Verrucous carcinoma was first used by Ackerman in 1948 as a specific term to describe the slow-growing, fungating and verrucous variant of squamous cell carcinoma. The clinicalappearance of verrucous carcinoma is distinguished difficultly from verrucous hyperplasia and squamous cell carcinoma. Histopathologically, it shows a hyperplastic lesion with hyperortho- and/or parakeratosis and blunt invasion of well polarized epithelial pegs. It is also difficult to didinguished from verrucous hyperplasia and other benign papillary lesions. There is much confusion in literature as to the etiologic factors and appropriate therapeutic method. In this clinic study, seventy-three cases of oral verrucous carcinoma were retrospectively collected from Kaohsiung Medical University Hospital from 1992 to 1997 for clinic study. Nearly all reports in Western countries found a connection between the development of verrucous carcinoma and the use of tabacco. The present study revealed betel quid chewing as the most possible etiologic factor for oral verrucous carcinoma in Taiwan area. The most common site of occurrence of oral verrucous carcinoma was the buccal mucosa followed by the lip and tongue. Males are significantly predominant. The mean age of occurrence in Taiwan was seem younger than those of Western reports. The recurrent rate was high whether treated by surgery and/or radiotherapy. Terefore, a close postoperative follow-up is required. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。