查詢結果分析
相關文獻
- Simplified 丨C-Urea Breath Test for the Diagnosis of Helicobacter Pylori Infection--The Availability of without Fasting and without Test Meal
- 漫談幽門螺旋桿菌感染及基層醫療之對策
- 胃幽門螺旋桿菌感染的未來展望
- Follow-up of Helicobacter Pylori Status by Using 丨C-Urea Breath Test in Nonulcer Dyspeptic Patients after Eradication Therapy
- A Comparison of the Efficacy between Denol-Based and Zantac-Based Triple Therapy for Recurrent Duodenal Ulcer Accompanied with Helicobacter Pylori Infection
- 幽門螺旋桿菌感染治療之指導方針
- Comparison of Three Different Non-invasive Methods for Detecting Helicobacter Pylori Infection in Children
- 胃腸科醫師及其助手的幽門螺旋桿菌感染之職業風險
- 根除幽門螺旋桿菌之病例用藥探討
- Clinical Utility of Histological Examination of Gastric Ulcer Margin to Diagnose Helicobacter Pylori Infection
頁籤選單縮合
題名 | Simplified 丨C-Urea Breath Test for the Diagnosis of Helicobacter Pylori Infection--The Availability of without Fasting and without Test Meal=簡化之碳-13尿素呼氣法用以診斷幽門螺旋桿菌感染--不空腹及不需試驗餐之可行性 |
---|---|
作者 | 王文明; 李瑞成; 吳登強; 陳立宗; 劉景勳; 彭健芳; 丁慧枝; 陳章義; 詹昌明; | 書刊名 | The Kaohsiung Journal of Medical Sciences |
卷期 | 16:12 2000.12[民89.12] |
頁次 | 頁607-613 |
分類號 | 415.5 |
關鍵詞 | 碳-13尿素呼氣法; 幽門螺旋桿菌感染; 試驗餐; 丨C-urea breath test; Helicobacter pylori; Test mea; |
語文 | 英文(English) |
中文摘要 | 傳統的碳-13尿素呼氣法用以檢查幽門螺旋桿菌感染,在施行時需要空 腹及喝試驗餐以延長胃排空,本研究乃評估不需空腹及試驗餐是否可行。共計連 續105個病人接受內視鏡檢查,並以尿素脢試驗,細菌培養及組織病理檢查來確 定幽門螺旋桿菌的存在。每一個病人都接受四種不同狀況的實驗方式,包括實驗 I:空腹及喝100cc鮮奶之試驗餐。實驗II:不空腹(一般飲食)及喝試驗餐。 實驗III:空腹但沒有喝試驗餐。實驗IV:不空腹也不喝試驗餐,每個實驗在喝 下碳-13尿素之後15分鐘收集呼氣樣本以計算其過剩之碳-13比值。結果有61 個幽門螺旋桿菌陽性及44個陰性例,根據ROC曲線以3.0,4.0,3.5及4.0分別 為四種實驗之界限值,結果實驗I之靈敏度及特異性各為100%及95%,其他三 種之靈敏度各為98% ,98%及100%,特異性各為95%,98%及95%。我們的結 論認為當界限值訂為4.0 per mil時碳-13尿素呼氣法可以省略空腹及喝試驗餐的 程序,這種簡化程序的碳-13尿素呼氣法 ( 不必空腹、不喝試驗餐,在喝下碳-13 尿素後15分鐘收集樣本 ),用在臨床診斷幽門螺旋桿菌感染是一種簡單可行的 方法。 |
英文摘要 | The conventional 13C-urea breath test (13C-UBT) for detecting Helicobacter pylori infection was performed during fasting state and with a test meal to delay gastric emptying during the test. For the convenience of propagating this test, we assessed the availability of non-fast and without test meal in 13C-UBT for the diagnosis of H. pylori infection. One hundred and five consecutive patients who received endoscopic examination were studied. All of them received endoscopic biopsy for urease test, culture and histopathology to determine whether there was a presence of H. pylori infection. Each patient received four separate 13C-UBT under the following four testing conditions. Test I)fasting state with test meal (100ml fresh milk), Test II)non-fast(taking usual food)but with test meal, Test III)fasting state without test meal, and Test IV)non-fast and without test meal. The excess δ13CO2 values were calculated via the breathed samples that were collected at 15 minutes after ingestion of 13C-urea. There were 61 H. pylori positive and 44 negative patients in this study, with an excess δ13CO2 values 3.0, 4.0, 3.5 and 4.0 as a cut-off value in the four tests respectively, according to the ROC curve. The results of test I, a conventional procedure, had a good correlation with the gold standard. The sensitivity and specificity were 100% and 95% respectively. The alternative procedures in other tests also have high sensitivity and specificity at 15-minute detecting time. The sensitivity of the tests II、III and IV at 15-minute detecting times were 98%, 98% and 100%, and the specificities of those were 95%, 98%and 95% respectively. We therefore suggest that fasting and test meal possibly be omitted when the cut-off value is 4.0 per mil in the simplified 13C-UBT (non-fast and without test meal, and detection at 15 minutes after ingestion of 13C-urea) which is a simple and available procedure for clinical diagnosis of H. pylori infection. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。