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題名 | 具有易流血特質之單一類上皮細胞型Spitz痣--病例報告及文獻回顧=Pure Epithelioid Spitz Nevus with Easily Bleeding Character--A Case Report & Literature Review |
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作者姓名(中文) | 蕭晨隆; 溫素瑩; | 書刊名 | 中華皮膚科醫學雜誌 |
卷期 | 18:3 2000.09[民89.09] |
頁次 | 頁223-228 |
分類號 | 415.78 |
關鍵詞 | 單一類上皮細胞型Spitz痣; 化膿性肉芽腫; Pure epithelioid Spitz nevus; Pyogenic granuloma; Vascular proliferation; |
語文 | 中文(Chinese) |
中文摘要 | Spitz痣為一種罕見的良性皮膚腫瘤,組織病理學上可分為兩型,一型由梭狀細胞組成,另一型則由梭狀細胞與類上皮細胞混合而成,觀諸文獻,甚少有單一類上皮細胞形成之Spitz痣。本文報告一二十四歲男性,於右大腿外側出現一表面光滑具彈性之紅色結節,大小為0.8 × 0.8 × 0.5cm,有易流血之特質,並曾有一次較大量出血的經驗,臨床上看似化膿性肉芽腫,其組織病理顯示許多由單一類上皮細胞組成之細胞巢,細胞巢的大小由病灶淺部至深部依序遞減,這些類上皮細胞呈S-100蛋白質陽性反應,細胞巢間並有大量血管增生,為一罕見由單一類上皮細胞組成之Spitz痣。 |
英文摘要 | Spitz nevus is a rare benign skin tumor. Histologically it may be classified as spindle cell nevus and mixed cell type of spindle and epithelioid cell. Pure epithelioid Spitz nevus is rare. A 21-year-old male had a 0.8 × 0.8 × 0.5cm smooth-surfaced, elastic, red-brownish, dome-shaped nodule over the lateral aspect of the right thigh and suffered from one episode of massive bleeding. Clinically it resembled a pyogenic granuloma. Histopathological examination of the lesion showed nests composed of pure epithelioid cells, which are S-100 positive. Massive vascular proliferation was also found. It was a rare Spitz nevus of pure epithelioid cells type. |
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