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題名 | 壞疽性膿皮病合併骨髓分化不良症候群=Pyoderma Gangrenosum Associated with Myelodysplastic Syndrome |
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作者姓名(中文) | 邱足滿; 楊國材; 張正雄; | 書刊名 | 中華皮膚科醫學雜誌 |
卷期 | 18:3 2000.09[民89.09] |
頁次 | 頁211-218 |
分類號 | 415.725 |
關鍵詞 | 壞疽性膿皮病; 骨髓分化不良症候群; Pyoderma gangrenosum; Myelodysplastic syndrome; |
語文 | 中文(Chinese) |
中文摘要 | 壞疽性膿皮病是一個少見、化膿性、有獨特臨床表徵的皮膚疾病。我們在此報告一位62歲女性病人,雙側小腿有廣泛疼痛性潰瘍,至本院感染科住院前已有11個月病史,在各醫院以感染性潰瘍治療(包括手術切除)均不見改善且病灶愈加擴大。經皮膚切片檢查、微生物培養檢查、其特殊臨床表徵及病程表現,我們診斷為壞疽性膿皮病。在全身性投與類固醇後,潰瘍逐漸癒合,且疼痛感亦大幅減輕,因此出院於門診繼續治療。然而兩天後患者因發燒、泛血球低下而再度入院,進一步檢查出病人罹患克列伯氏肺炎球菌肺炎及骨髓分化不良症候群。在抗生素及類固醇治療下,肺部情況穩定且潰瘍亦繼續癒合遺留篩狀疤痕。患者目前於血液科門診繼續追蹤治療。本文對壞疽性膿皮病與骨髓分化不良症候群的關係加以討論。 |
英文摘要 | Pyoderma gangrenosum(PG)is an uncommon, ulcerative, cutaneous disorder with distinctive clinical characteristics. We report a 62-year-old woman who had had extensive painful ulcers over bilateral calves for 11 months when she was admitted to our hospital. Although she had been treated as having infectious ulcers(including surgical excision)at other hospitals, but the ulcers continued to aggravate. According to the findings from the skin biopsy, the microbial culture results, the characteristics of the ulcers, and the clinical course, she was diagnosed to have pyoderma gangrenosum. With systemic steroid treatment, the ulcers healed gradually and the painful sensation was greatly relieved. Therefore she was discharged and being followed at OPD. However she was readmitted 2 days later due to fever and pancytopenia. With further examinations, she was diagnosed to have Klebsiella pneumoniae pneumonia and myelodysplastic syndrome(MDS). Under treatment with antibiotics and systemic steroid, the condition of the lung was improved and the ulcers healed gradually, leaving cribriform scars. In this report, we will discuss the relationship between PG and MDS. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。