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題 名 | Rhabdomyosarcoma: A Case Report=橫紋肌肉瘤:一病例報告 |
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作 者 | 范洪春; 洪志興; 阮春榮; 李明勇; 喻永生; 錢新南; | 書刊名 | 醫學研究 |
卷 期 | 20:5 2000.04[民89.04] |
頁 次 | 頁237-244 |
分類號 | 415.138 |
關鍵詞 | 橫紋肌肉瘤; 胚胎型; Rhabdomyosarcoma; Embryonal type; |
語 文 | 英文(English) |
中文摘要 | 橫紋肌肉瘤(rhabdomyosarcoma)是一種惡性腫瘤,源自屬於黃紋肌的中胚層細胞,任何部位只要有橫紋肌的地方都可發生;任何年齡都可能發生,好發生小孩及年輕人,是15歲以下最常見的軟組織惡性腫瘤。約佔小孩所有癌症的6%,其發生率約每一百萬人口有8個病例。由多位腫瘤學者及各兒童腫瘤研究團體共同成立橫紋肌肉瘤合作研究(Intergroup Rhabdomyosarcoma Study; IRS),綜合組織病理、診斷與分期,採用外科手術、放射治療及化學治療的多樣式治療(multi-modality therapy)的治療計畫下,使5年以上存活率提高至70%。在組織學上,橫紋肌肉瘤主要是以小圓形細胞組成,不易診斷。目前依形態分為四種,胚胎型(embryonal)、肺泡型(alveolar)、混合型(mixed)及多形型(plemorphic)。橫紋肌肉瘤最常見為胚胎型,通常預後最好,最少轉移。本篇報告一例因誤治療發生轉移而死亡的胚胎型橫紋肌肉瘤病患,並對此類型之癌症做文獻回顧。 |
英文摘要 | In this paper, a 4-year-old boy of rhabdomyosarcoma (RMS) confirmed by excisional biopsy is reported. The patient was initially sent to a local medical clinic due to a mass about 2 cm in diameter over the left mandibular angle. After one week of conservative treatment, he received excisional biopsy at Chang Gung Memorial Hospital, where embryonal type rhab-domysarcoma was diagnosed. The mass grew rapidly after the patient’s family refused any further treatment. Four months later, the patient was referred to our Pediatric Department for further evaluation and management of the tumor. After a course of chemotherapy and radiotherapy, partial shrinkage of the tumor was achieved. However, he died of rapid tumor progression because the tumor was very extensive. Biologic behavior of this tumor will be reviewed in this paper. |
本系統中英文摘要資訊取自各篇刊載內容。