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相關文獻
- Dexamethasone Alone Does Not Prevent Postoperative Nausea and Vomiting in Women Undergoing Dilatation and Curettage: A Comparison with Droperidol and Saline
- Failure of Prevention Against Postoperative Vomiting by Ondansetron or Prochlorperazine in Patients Undergoing Gynecological Laparoscopy
- 手術後噁心、嘔吐之防治策略
- Rolapitant對化學治療引起噁心嘔吐的檢視
- 身體移動與手術後嘔吐的關係
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題名 | Dexamethasone Alone Does Not Prevent Postoperative Nausea and Vomiting in Women Undergoing Dilatation and Curettage: A Comparison with Droperidol and Saline=單獨使用 Dexamethasone 無法預防子宮刮除術後之噁心及嘔吐:與 Droperidol 及生理食鹽水比較 |
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作者 | 曾劍英; 崔子軒; 湯兆舜; 何善臺; 王志中; Tzeng, Jann-inn; Tswei, Tze-shen; Tang, Chao-shun; Ho, Shung-tai; Wang, Jhi-joung; |
期刊 | 麻醉學雜誌 |
出版日期 | 20000900 |
卷期 | 38:3 2000.09[民89.09] |
頁次 | 頁137-142 |
分類號 | 416.5 |
語文 | eng |
關鍵詞 | 子宮刮除術; 手術後嘔吐; 嘔心; Surgery: dilation and curettage; Postoperative nausea and vomiting; Dexamethasone; |
中文摘要 | 背景:本研究的目的在評估以dexamethasone用來預防子宮刮除術後心及嘔吐的發生。Droperidol及生理食鹽水被用來作為對照組。方法:共160位(每組40位)接受子宮刮除術之漏女參與本次隨機,變盲及有對照組之研究。在麻醉誘導前第一組接受靜脈注射dexamcthasones毫克,第二組接受droperido11.25毫克,第三組接受droperido11.25毫克及dexamcthasones毫克,第四組接受生理食鹽水靜脈注射。結果:我們發現麻醉前給予dexamethasone無法預防手術後之德心及嘔吐的發生。而在手術後的24小時內,droperidol有預防效果,其術後德心及嘔吐的發生率為25%(P<0.05)。當以droperidol加dexamcthasone合併使用时,預防效果更佳,除了手术0至24小时內有效外,在2至24小时內也是最有效的一组。結論:我們認為單獨使用dexamcthasonc無法預防子宮刮除術後之德心及嘔吐,而droperidol為有效,當以dexamethasone合併dexamcthasone使用时效果最好。 |
英文摘要 | Background: The aim of this study was to evaluate the prophylactic effect of dexamethasone on postoperative nausea and vomiting (PONV) in women undergoing dilatation and curettage. Droperidol and saline were served as control. Methods: One hundred and sixty women (n=40 in each group) undergoing dilatation and curettage under intravenous anesthesia were enrolled in this randomized, double-blinded, placebo-controlled study. Immediately before the induction of anesthesia, group 1 patients received i.v. dexamethasone 8 mg; group 2 patients received i.v. droperidol 1.25 mg; group 3 patients received Lv. droperidol 1.25 mg and dexamethasone 8 mg, and group 4 received i.v. saline. Results: We found that dexamethasone alone did not reduce the incidence of PONY in a 24 h postoperative period. Droperidol was effective for this purpose with incidence of PONV of 25% (P <0.05). A combination of droperidol and dexamethasone was also effective and was the most effective regimen during the postoperative period of 2 24 h. Conclusions: We conclude that dexamethasone (8 mg) alone does not prevent PONV in women undergoing dilatation and curettage. Droperidol is effective. Dexamethasone enhances the antiemetic effect of droperidol. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。