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題名 | Enteric Adenovirus Infection in Children in Taipei=臺北地區兒童腸道腺病毒感染之研究 |
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作者 | 林曉娟; 高全良; 呂俊毅; 李君男; 邱婷芳; 李秉穎; 曾馨儀; 徐慧玲; 李慶雲; 黃立民; | 書刊名 | 微免與感染雜誌 |
卷期 | 33:3 2000.09[民89.09] |
頁次 | 頁176-180 |
分類號 | 417.513 |
關鍵詞 | 兒童; 腸道腺; 病毒感染; Adenovirus types 40 and 41; Diarrhea; Enteric adenovirus; Gastroenteritis; Taipei; |
語文 | 英文(English) |
英文摘要 | Enteric adenoviruses (EAds), including type 40 (Ad40) and 41 (Ad41), can cause acute and severe diarrhea in young children. To delineate the epidemiological features of pediatric EAds infection in Taiwan, we conducted a retrospective study of all cases of EAds gastroenteritis in children treated at National Taiwan University Hospital for the period from July 1993 to December 1997. Stool samples were tested for the presence of Ad40 or Ad41 by enzyme immunoassay (EIA). A total of 64 cases of EAds infection in 63 children aged from 8 days to 81 months old with a median age of 9.5 months treated during the study period were identified. The male-to-female ratio was 1.63 (39/24). No obvious seasonal clustering of EAds cases was noted. Most patients (76.6%) were infected before the age of 2 years. Clinical features included diarrhea (96.9%), fever (54.7%), vomiting (45.3%), mild dehydration (43.8%), symptoms of upper respiratory tract infection (21.9%), and abdominal pain (12.5%). Analysis of fecal samples in patients with diarrhea showed watery diarrhea in 72.2%, diarrhea with mucus in 20%, diarrhea with blood in 3.1% and diarrhea with mucus and blood in 1.6% of all patients. Nearly one-half (43.5%) of the patients had diarrhea for more than 7 days. Thirty-seven patients (57.8%) were hospitalized due to gastroenteritis or other unrelated diseases, and 11 patients (17.2%) acquired enteric adenovirus infection during hospitalization for other underlying disease. Twelve patients (18.8%) had mixed infections, which included rotavirus, respiratory syncytial virus (RSV) and Salmonella species. There were no deaths in this series. The findings of this study suggest that EAds are important etiologic microbes of pediatric gastroenteritis. |
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