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來源資料
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題 名 | The Localized Castleman's Disease: A Report of Five Cases=局限性卡所門氏病:五例病例報告 |
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作 者 | 林雍球; 楊適生; 莊政諺; 謝聖怡; 夏君毅; 徐中平; 陳志毅; | 書刊名 | 中華民國外科醫學會雜誌 |
卷 期 | 33:5 民89.09-10 |
頁 次 | 頁223-228 |
分類號 | 416.22 |
關鍵詞 | 局限性卡所門氏症; Castleman's disease; Giant lymph node hyperplasia; Angiofollicular lymph node hyperplasia; |
語 文 | 英文(English) |
中文摘要 | 局限性卡所門氏病是一種罕見的良性腫瘤;通常病患除了在胸部X光檢查意外發現有一界線明確的軟組織腫瘤外,無明顯症狀:因此手術切除對於診斷及治療是必要的。本篇主冒為回顧本院十年內以外科手術治療局限性卡所門氏病患的經驗檢討。在放射線檢查方面,所有病人胸部X光皆可發現縱隔腔異常腫塊;其中四例的病灶在電腦斷層掃瞄檢查中經注射顯影劑後,呈現均質性、顯像加強的單一、界線明確之軟組織腫瘤;僅有一例呈現瀰漫性病灶並包圍著兩側頭臂靜脈、上腔大靜脈及升主動脈。在治療方面,前四例接受傳統胸腔切開術以切除腫瘤;而另以正中胸骨切開術對瀰漫性病灶進行減體積手術。有三位病人於術後接受輔助性放射線治療:一例是由於腫瘤不完全切除,一例則是由於局部復發兩次,另一例為疑似不完全切除,所有病人在最後一次追蹤檢查皆無疾病復發現象。 一般而言,局限性卡所門氏病以外科切除術即可根治;然而對於某些無法完全切除的腫瘤或疑似不完全切除者,則可施予輔助性放射線治療。 |
英文摘要 | Localized Castleman's disease is a rare benign disorder which usually presents as an intrathoracic well-defined soft tissue mass without any symptoms. Surgical resection is mandatory for differential diagnosis and treatment. The purpose of this study was to present our surgical experiences in the management of localized Castleman's disease. From August 1988 through March 1999, five patients (4 men, 1 woman; age range, 18-56 years, mean age: 43 years) with final diagnosis of Castleman's disease were treated surgically at Taichung Veterans General Hospital. We reviewed the medical records of these five patients, including general data, clinical presentation, radiological findings, treatment and clinical follow-up. Abnormal mediastinal mass lesions were found on chest roentgenogram in all five patients. In four patients, mass lesions demonstrated as well-defined, solitary soft tissue masses in the mediastinum which were homogenously enhanced after contrast infusion on computed tomography (CT) scan. In the remaining one patient, soft tissue mass infiltrated the bilateral brachiocephalic veins, superior vena cava and ascending aorta. The four patients with well-defined soft tissue mass received conventional thoracotomy for tumor resection. The patient with infiltrating soft tissue mass underwent median sternotomy for debulking surgery. Adjuvant radiotherapy was administered to three patients, one for incomplete resection and the remaining two for uncertainty of complete resection. All of the patients were disease-free at the time of last follow-up. Generally, localized Castleman 's disease can be cured by surgical resection. If complete resection is not possible, irradiation is a good choice as adjuvant therapy. |
本系統中英文摘要資訊取自各篇刊載內容。