頁籤選單縮合
題名 | Intravesical Mitoxantrone in Superficial Bladder Cancer=表淺性膀胱癌膀胱內灌注Mitoxantrone |
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作者 | 江博暉; 江金培; | 書刊名 | The Kaohsiung Journal of Medical Sciences |
卷期 | 16:2 2000.02[民89.02] |
頁次 | 頁91-94 |
分類號 | 415.837 |
關鍵詞 | 表淺性膀胱癌; Bladder neoplasms; Intravesical; Mitoxantrone; |
語文 | 英文(English) |
中文摘要 | 總共有 25 位表淺性膀胱癌的病人在經尿道切除腫瘤後以 mitoxantrone (10 毫 克溶於 50 毫升生理食鹽水中)每週作膀胱內灌注,共連續 6 週。 在經過平均 12 個月的 追蹤,總共 76% 的病人沒有復發, 其中第一次得膀胱癌的病人有 69%,而以前曾得到者有 89% 沒有復發。這結果與其它預防性抗癌藥比起來,顯然是不錯的。大部份的病人沒有嚴重 的副作用,而僅有 2 位病人有第三度的局部副作用。 我們認為 mitoxantrone 在膀胱內化 學治療中是有效且安全的藥物。 |
英文摘要 | Twenty-five patients with Ta-T�睏ransitional cell carcinoma of the bladder were treated by transurethral resection (TUR) followed by intravesical chemoprophylaxis with mitoxantrone (10 mg diluted in 50 ml normal saline) administered weekly for 6 weeks. After a mean follow-up of 12 months, 76% of patients in the whole group, 69% in the newly diagnosed patients and 89% in the group of previously relapsed patients remained relapse free. These rates compare favorably with the other prophylactic agents available. Therapy was well tolerated in most patients, with only two patients reporting grade 3 local toxicity. We conclude that mitoxantrone is an effective and safe agent for intravesical chemotherapy. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。