查詢結果分析
來源資料
相關文獻
- Lethal Midline Granuloma: Report of Three Cases
- 血管免疫芽細胞性T細胞淋巴瘤
- Steroid-responsive Primary T-cell Lymphoma in the Brain: Report of a Case
- Cutaneous Cytomegalovirus Infection in a Patient with T-cell Lymphoma--A Case Report and Literature Review
- Malignant Lymphomas of Sinonasal Region, Including Cases of Polymorphic Reticulosis: A Retrospective Clinicopathologic Analysis of 34 Cases
- T-cell Lymphoma Involved Liver and Terminal Ileum Complicated with Reactive Hemophagocytic Syndrome: Report of a Case
- Enteropathy-associated T-Cell Lymphoma of the Jejunum Complicated with Intestinal Perforation
- 合併腸道病變之T細胞淋巴瘤
- Pathogenesis of Epstein-Barr Virus-Associated Hemophagocytic Syndrome in T Cell Lymphoma
- Sinonasal NK/T-cell Lymphoma with Upper Gastrointestinal Bleeding: A Case Report
頁籤選單縮合
題 名 | Lethal Midline Granuloma: Report of Three Cases=致命性中線肉芽腫的臨床與病理表徵:三例報告 |
---|---|
作 者 | 盧心玉; 陳維仁; 邢福柳; | 書刊名 | 長庚醫學 |
卷 期 | 23:2 2000.02[民89.02] |
頁 次 | 頁99-106 |
分類號 | 416.94 |
關鍵詞 | 致命性中線肉芽腫; T細胞淋巴瘤; Lethal midline granuloma; T-cell lymphoma; |
語 文 | 英文(English) |
英文摘要 | Lethal midline granuloma (LMG) is a rare clinical entity characterized by progressive relentless ulcerations and necrosis of midfacial structures. It occurs more frequently in Oriental than in Western populations with no demonstrable etiology. Treatment and outcome for cases differ, but their pathological distinction may not always be possible from routine biopsy specimens. The histological features often seen include widespread coagulative necrosis, heavy inflammatory infiltrates, and atypical pleomorphic cells. However, the paucity of these atypical cells in biopsy specimens and the degree of necrosis can make the diagnosis of a neoplastic lesion very difficult. Because of the progress in pathology methodology including immunohistochemistry, most cases have been proven to be malignant lymphomas of T-cell lineage. We present 3 patients for whom an initial clinical diagnosis of LMG was made. From their several oral biopsies and nasal specimens, difficulties were encountered in differentiating "midline granuloma" from other possible diseases using histomorphological criteria alone. After extensive evaluations, malignant T-cell lymphoma was the specific disease entity identified in only one case by cell membrane immunostaining technique. A literature review was carried out, and recent concepts of the etiology and pathogenesis of this disease are presented. |
本系統中英文摘要資訊取自各篇刊載內容。